Synovial Tissue Biopsy Research [PDF]
Frontiers in Medicine, 2019 Synovial tissue is a key structure in diarthrodial joints and is the primary target of inflammation in autoimmune arthritis. The study of synovial tissue has developed significantly in the last two decades as arthroscopic and ultrasonographic techniques ...
Douglas J. Veale
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Retrograde Synovial Biopsy of the Knee Joint Using a Novel Biopsy Forceps
Arthroscopy Techniques, 2014 Synovial biopsies of the knee joint are commonly performed arthroscopically with the patient under full or regional anesthesia. To overcome the effort, costs, and potential risks of surgery, we developed an office-based technique for retrograde synovial ...
Thomas Hügle, M.D., Ph.D. +9 more
doaj +3 more sources
Is there a role of synovial biopsy in drug development? [PDF]
BMC Musculoskelet Disord, 2016 Rheumatoid arthritis (RA) is an autoimmune disease which causes significant pain, joint deformity, functional disability. The pathological hallmark of RA is inflammation of the synovium characterized by involvement of inflammatory and resident stromal ...
Filkova M, Cope A, Mant T, Galloway J.
europepmc +4 more sources
Synovial Tissue Biopsy Collection by Rheumatologists: Ready for Clinical Implementation? [PDF]
Frontiers in Medicine, 2019 Synovial tissue from arthritis patients is increasingly used for both basic pathophysiological and clinical translational research. This development has been spurred by the development of biotechnological techniques for analysis of complex tissues and ...
Marijn Smits +2 more
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Ultrasound-guided synovial biopsy. [PDF]
Br J Radiol, 2016 Ultrasound-guided needle biopsy of synovium is an increasingly performed procedure with a high diagnostic yield. In this review, we discuss the normal synovium, as well as the indications, technique, tissue handling and clinical applications of ultrasound-guided synovial biopsy.
Sitt JC, Griffith JF, Wong P.
europepmc +5 more sources
Preoperative Synovial Fluid Cultures, and Biopsy Cultures After Dry Tap Aspiration, Are Valuable in Diagnosing a Periprosthetic Joint Infection: A Retrospective Study [PDF]
MicroorganismsPeriprosthetic joint infection (PJI) is a devastating complication after total hip arthroplasty. Synovial fluid aspiration and preoperative tissue biopsy cultures can be helpful diagnostic tools for PJI.
Ewout S Veltman +2 more
exaly +4 more sources
Definitions, 2020 The synovium is the major target tissue of inflammatory arthritides such as rheumatoid arthritis (RA). The study of synovial tissue has advanced significantly over a number of decades from arthroplasty, blind needle biopsy and more recently facilitated ...
semanticscholar +2 more sources
Arthroscopic Guided Synovial Biopsies [PDF]
Frontiers in Medicine, 2021 Synovial tissue can be safely and reliably collected for research and clinical purposes using arthroscopy. This technique offers the obvious advantage of allowing direct visualization, and targeted biopsy of specific areas of interest within the joint ...
Carl Kieran Orr +5 more
doaj +4 more sources
Efficacy, Safety, and Sample Quality of Ultrasound‐Guided Synovial Needle Biopsy in Clinical Practice and Research: A Prospective Observational Study [PDF]
Arthritis care & research, 2020 To study the efficacy, tolerability, safety, and sampling variation of ultrasound (US)–guided synovial biopsies performed in clinical practice and research.
V. Romão +11 more
semanticscholar +2 more sources
The access route through the anatomical snuffbox in ultrasound-guided synovial biopsy of the wrist allows for a safe and effective collection of tissue samples in inflammatory arthritis [PDF]
Arthritis Research & Therapy, 2023 Background A proof-of-concept study to evaluate the feasibility and safety of minimally invasive ultrasound (US)-guided synovial biopsy of the radiocarpal (RC) joint using the anatomical snuffbox as an access route.
Ludovico De Stefano +7 more
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