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OBJECTIVE: To determine the tolerability, safety and yield of synovial tissue in an early arthritis cohort using a minimally invasive, ultrasound (US)-guided, synovial biopsy technique in small, medium and large joints.
S. Kelly +12 more
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Best Practice and Research in Clinical Rheumatology, 2005
In patients with arthritis, synovial tissue is easily accessible for analysis. Blind needle biopsy is a simple and safe procedure. Arthroscopic biopsy is also safe, it allows access to most sites in the joint and it can provide adequate tissue for extensive laboratory investigations, both before and after successful therapy.
Paul P Tak
exaly +3 more sources
In patients with arthritis, synovial tissue is easily accessible for analysis. Blind needle biopsy is a simple and safe procedure. Arthroscopic biopsy is also safe, it allows access to most sites in the joint and it can provide adequate tissue for extensive laboratory investigations, both before and after successful therapy.
Paul P Tak
exaly +3 more sources
Diagnostic value of blind synovial biopsy in clinical practice.
OBJECTIVE: To assess the diagnostic value of blindly performed synovial biopsies in carefully selected patients with unclassified arthritis. METHODS: Synovial tissue was obtained blindly under local anaesthesia.
Johanna M W Hazes
exaly +2 more sources
Pediatric Blood & Cancer, 2022
The possible application of gene fusion transcripts as tumor‐specific noninvasive liquid biopsy biomarkers was investigated in blood plasma from patients with alveolar rhabdomyosarcoma (ARMS) and synovial sarcoma (SS).
S. Stegmaier +10 more
semanticscholar +1 more source
The possible application of gene fusion transcripts as tumor‐specific noninvasive liquid biopsy biomarkers was investigated in blood plasma from patients with alveolar rhabdomyosarcoma (ARMS) and synovial sarcoma (SS).
S. Stegmaier +10 more
semanticscholar +1 more source
2020
Abstract Synovial tissue is the primary tissue inflamed in rheumatoid arthritis. Initial studies of synovial biopsies were obtained during arthroplasty or using a needle to biopsy the joint percutaneously. Recently, small needle arthroscopy or ultrasonography guided techniques have become more widely available to visualize and ...
Douglas J. Veale, Ursula Fearon
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Abstract Synovial tissue is the primary tissue inflamed in rheumatoid arthritis. Initial studies of synovial biopsies were obtained during arthroplasty or using a needle to biopsy the joint percutaneously. Recently, small needle arthroscopy or ultrasonography guided techniques have become more widely available to visualize and ...
Douglas J. Veale, Ursula Fearon
openaire +1 more source
Synovial Membrane Punch Biopsy
Archives of Internal Medicine, 1961Biopsy material has proved to be of value in the investigation of many inflammatory and malignant disease processes. Examination of the synovial membrane by open biopsy, under anesthesia, has been performed by orthopedists for many years. Polley and Bickel, in 1951, 1,2 described an instrument for performing a closed punch biopsy.
S, SCHWARTZ, N, COOPER
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Ultrasound Guided Synovial Biopsy of the Wrist
Scandinavian Journal of Rheumatology, 1997Seven patients (4 female and 3 male, mean age 46) with arthritis of the wrist (n = 7) without known etiology were evaluated. High-definition ultrasound equipment was used for localization of synovial hypertrophy, suitable for ultrasound guided biopsy without risk. A 18-gauge diameter Tru-cut biopsy needle was used in an automated gun.
van Vugt, R.M. +2 more
exaly +4 more sources
Percutaneous Biopsy of the Synovial Membrane
Seminars in Musculoskeletal Radiology, 1997Techniques of percutaneous synovial biopsy under fluoroscopic control of large joints of the limbs (other than the knee) may be useful in arthritis of undetermined etiology especially when infection is considered. Main technical refinements include adequate selection of an optimal approach and biopsy site using new imaging methods, use of a Tru-Cut(R ...
Caroline, Parlier-Cuau +4 more
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How to perform and analyse synovial biopsies
Best Practice and Research in Clinical Rheumatology, 2009Although most of the rheumatologic diseases can be diagnosed based on clinical examination combined with additional laboratory and radiographic tests, histological examination of synovial tissue may lead to the correct diagnosis and adjustment of therapy when neoplastic or granulomatous disease, deposition disease, or infection in spite of negative ...
Paul P Tak, Danielle M Gerlag
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1982
More than 150 different diseases are known in which one or more joints may be affected (Huskisson and Dudley Hart 1973). The articular lesions may present the only or the principal symptom, or may be inconspicuous. In many the histopathological picture in the synovium is non-specific, in some typical, rarely it is pathognomonic.
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More than 150 different diseases are known in which one or more joints may be affected (Huskisson and Dudley Hart 1973). The articular lesions may present the only or the principal symptom, or may be inconspicuous. In many the histopathological picture in the synovium is non-specific, in some typical, rarely it is pathognomonic.
openaire +2 more sources

