Results 71 to 80 of about 2,164,308 (357)

Synovial fluid proteome in rheumatoid arthritis

Clinical Proteomics, 2016
Rheumatoid arthritis (RA) is a chronic autoinflammatory disorder that affects small joints. Despite intense efforts, there are currently no definitive markers for early diagnosis of RA and for monitoring the progression of this disease, though some of ...
M. Bhattacharjee, Lavanya Balakrishnan, S. Renuse, Jayshree Advani, R. Goel, G. Sathe, T. S. Keshava Prasad, B. Nair, R. Jois, S. Shankar, A. Pandey   +10 more
semanticscholar   +1 more source

An Organ‐on‐Chip Platform for Strain‐Controlled, Tissue‐Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis

Advanced Healthcare Materials, EarlyView.
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi, Anastasiya Börsch, Paola Occhetta, Robert Ivanek, Martin Ehrbar, Lisa Krattiger, Philipp Oertle, Marko Loparic, Ivan Martin, Marco Rasponi, Andrea Barbero   +10 more
wiley   +1 more source

The penetration of metronidazole into synovial fluid [PDF]

Postgraduate Medical Journal, 1982
Abstract Six patients with non-infected synovial effusions, associated either with inflammatory or degenerative arthropathy and requiring diagnostic or therapeutic aspiration, were given a short course of 400 mg metronidazole (Flagyl) 8-hourly for 3 doses.
M. I. D. Cawley, M. G. Sankey, M. A. Sattar, JE Holt, C. M. Kaye   +4 more
openaire   +3 more sources

Expression of hypoxia-inducible factor-1α in synovial fluid and articular cartilage is associated with disease severity in knee osteoarthritis

Experimental and Therapeutic Medicine, 2016
The aim of the present study was to examine hypoxia-inducible factor 1α (HIF-1α) levels in the synovial fluid and articular cartilage of patients with primary knee osteoarthritis (OA) and to investigate their association with the severity of disease.
Li-ming Qing, Pengfei Lei, Hao Liu, Jie Xie, Long Wang, Ting Wen, Yihe Hu   +6 more
semanticscholar   +1 more source

Responsive Polyelectrolyte Brushes in Applications: Functions, Stimuli, and Design Considerations

Advanced Materials, EarlyView.
With advances in the synthesis of polyelectrolyte brushes, these coatings of surface‐grafted chains find uses in an increasing number of applications. This review summarizes three core aspects of these brushes: how they introduce functionality to surfaces; how external stimuli influence their properties; and what practical considerations should be ...
Leon A. Smook, Andreas Dahlin, Karin Schroën, Sissi de Beer   +3 more
wiley   +1 more source

Determination of ratio of passing of flunixin meglumine into sinovial fluid [PDF]

Eurasian Journal of Veterinary Sciences
This experimental study was conducted to determine of ratio of passing of flunixin meglumine into synovial fluid. Five healthy dogs were usedas materials. Flunixin meglumine (FinadynR) was injected intramuscularly (1.1 mg/kg) to each dog.
Bünyamin Traş, Celal İzci, Muammer Elmas   +2 more
doaj  

Release of Active Peptidyl Arginine Deiminases by Neutrophils Can Explain Production of Extracellular Citrullinated Autoantigens in Rheumatoid Arthritis Synovial Fluid

Arthritis & Rheumatology, 2015
In the majority of patients with rheumatoid arthritis (RA), antibodies specifically recognize citrullinated autoantigens that are generated by peptidylarginine deiminases (PADs). Neutrophils express high levels of PAD and accumulate in the synovial fluid
J. Spengler, Bo Zo Lugonja, A. Ytterberg, R. Zubarev, A. Creese, M. Pearson, M. Grant, K. Lundberg, C. Buckley, P. Cooper, I. Chapple, D. Scheel-Toellner, Jimmy Ytterberg, Karolinska Institutet, Sweden Stockholm, M. Milward, K. Raza, A. Filer   +17 more
semanticscholar   +1 more source

Biomolecular Condensates as Emerging Biomaterials: Functional Mechanisms and Advances in Computational and Experimental Approaches

Advanced Materials, EarlyView.
Integration of computational and experimental approaches for deciphering the underlying mechanism of biomolecular condensates and potential biomaterials design (Created in Biorender. Raza, Z. (2025) https://BioRender.com/irgmeqi). Abstract Biomolecular condensates, a ubiquitous class of biomaterials found in living cells, have been shown to be ...
Qiang Zhu, Zahra Raza, Dzung Do‐Ha, Emma De Costa, Pavlina Sasheva, Luke McAlary, Hadi Mahmodi, Warwick P. Bowen, Lezanne Ooi, Irina Kabakova, Haibo Yu   +10 more
wiley   +1 more source

Serum versus synovial fluid interleukin-6 for periprosthetic joint infection diagnosis: a systematic review and meta-analysis of 30 diagnostic test accuracy studies

Journal of Orthopaedic Surgery and Research, 2022
Background Early and accurate detection of periprosthetic joint infection (PJI) after hip and/or knee arthroplasty remains challenging. This systematic review and meta-analysis of diagnostic test accuracy studies aimed to evaluate the diagnostic accuracy
Jian Li, Qian Zhou, Biquan Deng
doaj   +1 more source

Identification of crystals in synovial fluid [PDF]

Annals of the Rheumatic Diseases, 1999
Synovial fluids can contain a number of crystals and other particulate matter. Some of these, particularly monosodium urate monohydrate (MSUM) and calcium pyrophosphate dihydrate (CPPD) crystals, are pathogenic; others, including cholesterol and other lipid particles and the basic calcium phosphates (BCPs), including apatites, are of doubtful ...
A Swan, Paul Dieppe
openaire   +3 more sources