Background: Neurocytokines may upregulate or downregulate neuropathic pain. We hypothesized that dextrose (D-glucose) injections for therapeutic purposes (dextrose prolotherapy: DPT) in painful knee osteoarthritis (KOA) would favorably affect synovial ...
Gastón Andrés Topol +6 more
doaj +1 more source
Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins [PDF]
Introduction: Rheumatoid arthritis (RA) is an inflammatory disease, which results in destruction of the joint. The presence of immune complexes (IC) in serum and synovial fluid of RA patients might contribute to this articular damage through different ...
De Ceuleneer, Marlies +5 more
core +3 more sources
Multiscale modelling of fluid and solute transport in soft tissues and microvessels [PDF]
This study focuses on the movement of particles and extracellular fluid in soft tissues and microvessels. It analyzes modeling applications in biological and physiological fluids at a range of different length scales: from between a few tens to several ...
Lu, Yiling, Wang, Wen
core +2 more sources
Effects of ACL Reconstructive Surgery on Temporal Variations of Cytokine Levels in Synovial Fluid
Anterior cruciate ligament (ACL) reconstruction restores knee stability but does not reduce the incidence of posttraumatic osteoarthritis induced by inflammatory cytokines.
M. Bigoni +13 more
semanticscholar +1 more source
Optimized “In Vitro” Culture Conditions for Human Rheumatoid Arthritis Synovial Fibroblasts
The composition of synovial fluid in rheumatoid arthritis (RA) is complex and strongly influences the microenvironment of joints and it is an inseparable element of the disease.
Claudia Casnici +8 more
doaj +1 more source
On the Modeling of the Synovial Fluid [PDF]
Synovial fluid is a polymeric liquid which generally behaves as a viscoelastic fluid due to the presence of hyaluronan molecules. We restrict ourselves to the regime in which the fluid responds as a viscous fluid. A novel generalized power-law fluid model is developed wherein the power-law exponent depends on the concentration of the hyaluronan. Such a
Petra Pustějovská +3 more
openaire +1 more source
Differential patterns of PMN-elastase and type III procollagen peptide in knee joint effusions due to acute and chronic sports injuries [PDF]
In 38 traumatic knee joint effusions the proteolytic enzyme PMN-elastase (PMN-E) and the repair marker procollagen III aminoterminal peptide (PIIINP) were determined.
A Billing +29 more
core +1 more source
The liver X receptor pathway is highly upregulated in rheumatoid arthritis synovial macrophages and potentiates TLR-driven cytokine release [PDF]
<p>Objectives: Macrophages are central to the inflammatory processes driving rheumatoid arthritis (RA) synovitis. The molecular pathways that are induced in synovial macrophages and thereby promote RA disease pathology remain poorly understood.</
Ananth +42 more
core +1 more source
Human intestinal microbes can mediate development of arthritis – Studies indicate that certain bacterial nucleic acids may exist in synovial fluid (SF) and could be involved in arthritis, although the underlying mechanism remains unclear. To characterize
Yan Zhao +13 more
semanticscholar +1 more source
Aims: Synovial fluid white blood cell (WBC) count and percentage of polymorphonuclear cells (%PMN) are elevated at periprosthetic joint infection (PJI).
René Mihalič +3 more
doaj +1 more source

