Extracellular vesicles from platelet-poor plasma possess anti-inflammatory and anti-catabolic effects in chondrocytes stimulated with IL-1β or synovial membrane-conditioned media. [PDF]
Gulova S+7 more
europepmc +1 more source
Characterisation of the cell type-specificity of collagenase 3 mRNA expression in comparison with membrane type 1 matrix metalloproteinase and gelatinase A in the synovial membrane in rheumatoid arthritis [PDF]
Peter Petrow
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ABSTRACT Osteoarthritis (OA) is a highly prevalent chronic joint disorder affecting ~600 million individuals worldwide and is characterized by complex pain mechanisms that significantly impair patient quality of life. Challenges exist in accurately assessing and measuring pain in OA due to variations in pain perception among individuals and the ...
Shujaa T. Khan+10 more
wiley +1 more source
Single intra-articular injection of human synovial membrane MSC from grade IV knee osteoarthritis patient improve cartilage repair in OA rat model. [PDF]
Rahmadian R+4 more
europepmc +1 more source
Morphological and Molecular Features of Porcine Mesenchymal Stem Cells Derived From Different Types of Synovial Membrane, and Genetic Background of Cell Donors. [PDF]
Siengdee P+5 more
europepmc +1 more source
Effects of continuous intra-articular infusion of gentamicin on synovial membrane and articular cartilage in the tarsocrural joint of horses [PDF]
Timothy B. Lescun+4 more
openalex +1 more source
Macrophage Signaling Pathways in Health and Disease: From Bench to Bedside Applications
Macrophage functions in phagocytosis, tissue repair, immune regulation, and neuronal network protection. And graphic abract image in the attachment. ABSTRACT Macrophages exhibit remarkable functional plasticity by dynamically polarizing into proinflammatory or antiinflammatory subsets in response to microenvironmental cues. This duality underpins their
Yongquan Chi+6 more
wiley +1 more source
Influence of inflammation on the expression of microRNA-140 in extracellular vesicles from 2D and 3D culture models of synovial-membrane-derived stem cells. [PDF]
Pfeifer JPH+7 more
europepmc +1 more source
Angiopoietin expression in synovial membranes from patients with RA [PDF]
Malcolm Smith
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Autoimmune Diseases: Molecular Pathogenesis and Therapeutic Targets
This review provides a comprehensive overview of common autoimmune diseases, details clinical manifestations and summarizes the pathogenesis, including the breakdown of immune tolerance, initiation of autoimmune responses, and their progressive amplification.
Xiaoshuang Song+9 more
wiley +1 more source