Increase in Tryptase and Its Role in the Synovial Membrane of Overweight and Obese Patients with Osteoarthritis of the Knee. [PDF]
Takata K +9 more
europepmc +1 more source
ABSTRACT The evolving haemophilia care landscape has evolved with personalised prophylaxis, new coagulation factor molecules, non‐replacement therapies, and gene therapy, leading to significantly reduced bleeding frequency and haemophilic arthropathy burden.
Hortensia De la Corte‐Rodriguez +16 more
wiley +1 more source
Effect of moxibustion on the PINK1/Parkin pathway and mitophagy in rats with rheumatoid arthritis
ObjectiveTo observe the effect of moxibustion at “Shenshu” (BL23) and “Zusanli” (ST36) on the PTEN-induced putative kinase 1 (PINK1)/E3 ubiquitin ligase (Parkin) pathway and mitophagy in rats with rheumatoid arthritis (RA), so as to explore its possible ...
WANG Jie +7 more
doaj +2 more sources
Synovial Membrane Is a Major Producer of Extracellular Inorganic Pyrophosphate in Response to Hypoxia. [PDF]
Velot É, Sébillaud S, Bianchi A.
europepmc +1 more source
Increased elastic modulus of the synovial membrane in a rat ACLT model of osteoarthritis revealed by atomic force microscopy. [PDF]
Dai S +9 more
europepmc +1 more source
Emerging Roles of PSTPIP2 in Autoimmunity: From Mechanism to Therapeutic Implications
PSTPIP2 acts as a key brake on myeloid inflammation by suppressing IL‐1β‐driven signalling, macrophage dysregulation and inflammation‐associated bone remodelling. Its emerging roles in CRMO/CMO, rheumatoid arthritis, SAPHO syndrome and bullous pemphigoid support its potential as a biomarker and therapeutic target.
Erdong Zhang +9 more
wiley +1 more source
Extracellular vesicles from platelet-poor plasma possess anti-inflammatory and anti-catabolic effects in chondrocytes stimulated with IL-1β or synovial membrane-conditioned media. [PDF]
Gulova S +7 more
europepmc +1 more source
Repeated TMJ injury in mice demonstrated that greater injury severity and female sex exacerbate post‐traumatic TMJ degeneration. While short‐term nociceptor inhibition reduced pain without affecting degeneration, prolonged inhibition modestly attenuated degeneration, suggesting that persistent post‐traumatic pain contributes to TMJ osteoarthritis ...
Ishraq Alshanqiti +4 more
wiley +1 more source
Single intra-articular injection of human synovial membrane MSC from grade IV knee osteoarthritis patient improve cartilage repair in OA rat model. [PDF]
Rahmadian R +4 more
europepmc +1 more source
Genetic Susceptibility to Periodontitis
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley +1 more source

