Results 51 to 60 of about 46,096 (291)

HISTOMORPHOMETRIC ANALYSIS OF THE KNEE ARTICULAR CARTILAGE AND SYNOVIUM FOR METADIAPHYSEAL LEG LENGTHENING (EXPERIMENTAL-AND-MORPHOLOGICAL STUDY)

Travmatologiâ i Ortopediâ Rossii, 2013
The knee articular cartilage and synovial membrane have been studied for metadiaphyseal leg lengthening using the methods of light miscroscopy, computer morpho- and stereometry.
T. A. Stupina, N. A. Schoudlo, N. V. Petrovskaya, M. A. Stepanov   +3 more
doaj   +1 more source

Synovial Fluid of Patient With Rheumatoid Arthritis Enhanced Osmotic Sensitivity Through the Cytotoxic Edema Module in Synoviocytes

Frontiers in Cell and Developmental Biology, 2021
Rheumatoid arthritis (RA) is an autoimmune disease that causes inflammation of the synovial membrane ultimately leading to permanent damage in the affected joints.
Min Jeong Ji, Min Jeong Ji, Hee Jung Ryu, Jeong Hee Hong   +3 more
doaj   +1 more source

Sports-related changes of the synovial membrane [PDF]

Joints, 2014
the aim of this study is to differentiate the behavior of the synovial membrane in the presence of various stimuli in patients who practice sports.fifty one patients (30 males and 21 females, mean age 48 years, range 31-59 years) who actively practiced non-competitive sports underwent a biopsy of the synovial membrane during arthroscopic surgery ...
Manunta, Andrea F., Zedde, Pietro, Pisanu, Francesco, Marras, Francesco   +3 more
openaire   +4 more sources

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

Inertial and Linear Re-Absorption Effects on a Synovial Fluid Flow Through a Lubricated Knee Joint

Lubricants
This study examines the flow dynamics of synovial fluid within a lubricated knee joint during movement, incorporating the effect of inertia and linear re-absorption at the synovial membrane.
Abdul Majeed Siddiqui, Khadija Maqbool, Afifa Ahmed, Amer Bilal Mann   +3 more
doaj   +1 more source

Engineered Stem Cell Clusters for Extracellular Vesicles‐Mediated Gene Delivery to Rejuvenate Chondrocytes and Facilitate Chondrogenesis in Osteoarthritis Therapy

Advanced Science, EarlyView.
BMSCmotif+miR874/MS system is designed as a gene delivery platform utilizing engineered bone marrow mesenchymal stem cell (BMSC)‐derived extracellular vesicles (EVs) for intercellular communication to achieve sustained delivery of miRNA‐874‐3p. Rejuvenation of chondrocytes and promotion of chondrogenesis are achieved by inhibition of the NF‐κB pathway,
Yuezhou Wu, Yubo Feng, Fei Hu, Xu Zheng, Yurun Ding, Xuesong Liu, Shicheng Huo, Zhuocheng Lyu   +7 more
wiley   +1 more source

Fibrotic pathways and fibroblast-like synoviocyte phenotypes in osteoarthritis

Frontiers in Immunology
Osteoarthritis (OA) is the most common form of arthritis, characterized by osteophyte formation, cartilage degradation, and structural and cellular alterations of the synovial membrane.
Alexandra Damerau, Alexandra Damerau, Emely Rosenow, Dana Alkhoury, Frank Buttgereit, Frank Buttgereit, Timo Gaber, Timo Gaber   +7 more
doaj   +1 more source

Intra Articular Synovial Lipoma of the Right Tarsometatarsal Joint- A Rare Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2014
Intra articular synovial lipomas are very rare and only few cases have been reported till now. We are reporting a rare case of intra articular synovial lipoma of the tarsometatarsal joint in the right foot in a 38-year-old male who presented with dull ...
Pavithra. P, Arundhathi.S, C. R. Kodandaswamy   +2 more
doaj   +1 more source

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source

Effects of ultrasound therapy on the synovial fluid proteome in a rabbit surgery-induced model of knee osteoarthritis

BioMedical Engineering OnLine, 2019
Background Ultrasound (US) therapy may improve osteoarthritis symptoms. We investigated the effects of US on the synovial fluid (SF) proteome in a rabbit knee osteoarthritis (KOA) model to explore its therapeutic mechanisms.
Qinglu Luo, Shuangquan Ji, Zhimi Li, Tao Huang, Siqin Fan, Qin Xi   +5 more
doaj   +1 more source