Results 51 to 60 of about 2,099,395 (269)

Peptide-anchored neutrophil membrane-coated biomimetic nanodrug for targeted treatment of rheumatoid arthritis

Journal of Nanobiotechnology, 2023
Macrophage polarization determines the production of cytokines that fuel the initiation and evolution of rheumatoid arthritis (RA). Thus, modulation of macrophage polarization might represent a potential therapeutic strategy for RA.
Ni Yang, Miaomiao Li, Ling Wu, Yinhong Song, Shi Yu, Yingying Wan, Wenjing Cheng, Baoye Yang, Xiaoqin Mou, Hongfeng Yu, Jing Zheng, Xinzhi Li, Xiang Yu   +12 more
semanticscholar   +1 more source

Immunohistochemical Analysis of IL-1 Receptor 1 In the Discs of Patients with Temporomandibular Joint Dysfunction [PDF]

, 2018
Objective Temporomandibular joint dysfunction (TMD) may affect a patient’s quality of life, and one of the etiologies can be anterior disc displacement with reduction (ADDwR) and anterior disc displacement without reduction (ADDWoR).
Almeida, Luis Eduardo, Bosio, Jose A, Butcher, Seth, Doetzer, Andrea, Hresko, Kyle, Leonardi, Rosalia, Lorento, Carla, Sorenson, Adam, Tayebi, Lobat   +8 more
core   +2 more sources

Disuse histological changes of an unloading environment on joint components in rat knee joints

Osteoarthritis and Cartilage Open, 2019
Summary: Objectives: To clarify the effects of mechanical unloading on joint components, including the articular cartilage by knee compartments, synovial membrane, and the infrapatellar fat pad (IFP), using a hindlimb suspension rat model.
Ikufumi Takahashi, Taro Matsuzaki, Hiroshi Kuroki, Masahiro Hoso   +3 more
doaj   +1 more source

The Overexpression of NALP3 Inflammasome in Knee Osteoarthritis Is Associated with Synovial Membrane Prolidase and NADPH Oxidase 2

Oxidative Medicine and Cellular Longevity, 2016
Osteoarthritis is characterized by the presence of proinflammatory cytokines and reactive oxygen species. We aimed to clarify the role of prooxidant enzyme content at the synovial membrane level and how it correlates with the inflammatory process in ...
D. Clavijo-Cornejo, K. Martínez-Flores, Karina Silva-Luna, G. Martínez-Nava, J. Fernández-Torres, Y. Zamudio-Cuevas, Mónica Guadalupe Santamaría-Olmedo, Julio Granados-Montiel, C. Pineda, A. López-Reyes   +9 more
semanticscholar   +1 more source

Effects over time of two platelet gel supernatants on growth factor, cytokine and hyaluronan concentrations in normal synovial membrane explants challenged with lipopolysaccharide

BMC Musculoskeletal Disorders, 2015
BackgroundPlatelet-rich plasma (PRP) preparations are a common treatment in osteoarthritis (OA) and inflammatory synovitis. However, there is ambiguity regarding the ideal concentration of leukocytes and platelets in these preparations necessary to ...
Diana L. Ríos, C. López, M. Álvarez, I. Samudio, J. Carmona   +4 more
semanticscholar   +1 more source

Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis [PDF]

, 2009
Antibodies to citrulline-modifi ed proteins have a high diagnostic value in rheumatoid arthritis (RA). However, their biological role in disease development is still unclear.
Aho, Andersson, Auger, Baeten, Bella, Bettina Sehnert, Brunsberg, Burkhardt, Burkhardt, Bäcklund, Caspi, Chang, Chapuy-Regaud, Collaborative Computational Project, Number 4, DeLano, Dyson, Emsley, Emsley, Emsley, Estelle Bajtner, Foulquier, Girbal-Neuhauser, Giudicelli, Grab, Guy Serre, Harald Burkhardt, Hill, Hill, Hoffmann, Hüseyin Uysal, Kabsch, Kanazawa, Kidd, Krissinel, Kuhn, Kutty S. Nandakumar, Lefranc, Marjolein M.G.M. Thunnissen, Masson-Bessière, Masson-Bessière, Michaëlsson, Molberg, Murshudov, Nair, Nandakumar, Rantapää-Dahlqvist, Read, Reparon-Schuijt, Rikard Holmdahl, Robert Bockermann, Rosloniec, Schellekens, Schellekens, Schulte, Schwab, Stanfield, Stetefeld, Tarcsa, Uysal, van der Helm-van Mil, Vander Cruyssen, von Delwig, Vossenaar, Vossenaar, Vossenaar, Vossenaar, Winn, Yousfi Monod, Zong, Åke Engström   +69 more
core   +2 more sources

The Crucial Questions on Synovial Biopsy: When, Why, Who, What, Where, and How?

Frontiers in Medicine, 2021
In the majority of joint diseases, changes in the organization of the synovial architecture appear early. Synovial tissue analysis might provide useful information for the diagnosis, especially in atypical and rare joint disorders, and might have a value
Francesca Ingegnoli, Francesca Ingegnoli, Lavinia Agra Coletto, Lavinia Agra Coletto, Isabella Scotti, Isabella Scotti, Riccardo Compagnoni, Riccardo Compagnoni, Pietro Simone Randelli, Pietro Simone Randelli, Roberto Caporali, Roberto Caporali   +11 more
doaj   +1 more source

Specific biological responses of the synovial membrane to carbon nanotubes

Scientific Reports, 2015
Biological evaluation of carbon nanotubes (CNTs) is typically performed in the lung or abdominal cavity; however, biological reactions to CNTs are predicted to be markedly different in other tissues.
Hiroki Nomura, Seiji Takanashi, Manabu Tanaka, H. Haniu, Kaoru Aoki, M. Okamoto, Shinsuke Kobayashi, T. Takizawa, Yuki Usui, Ayumu Oishi, Hiroyuki Kato, N. Saito   +11 more
semanticscholar   +1 more source

True infliximab resistance in rheumatoid arthritis: a role for lymphotoxin α? [PDF]

, 2004
Background: The combination of methotrexate and the anti-tumour necrosis factor (TNF) antibody infliximab is a very effective treatment for rheumatoid arthritis (RA). However, a proportion of patients are not responsive to this treatment. Inefficacy may
Bingham, S.J., Buch, M.H., Conaghan, P., Emery, P., Quinn, M.A., Veale, D.   +5 more
core   +2 more sources

Synovial fluid over the centuries

Reumatismo, 2003
This review deals with the most meaningful historical topics on the study of synovial fluid, by starting from the Greco- Roman Medicine, up to Paracelsus (1493-1541), who introduced the term “synovia” to name the intra-articular humour.
P. Marson
doaj   +1 more source