Results 181 to 190 of about 2,054,522 (273)

Quantification of Vancomycin and Clindamycin in Synovial Tissue and Bone Using Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry. [PDF]

Ther Drug Monit
Holst AJ, Bahmany S, van Dorp ACJ, van Oldenrijk J, Bos PK, Veltman ES, de Winter BCM, Koch BCP.   +7 more
europepmc   +1 more source

IGF2BP3 Overexpression Accelerates Osteoarthritis Progression by Promoting Glycolysis via m6A‐Dependent Stabilization of ECM1 mRNA

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT N6‐methyladenosine (m6A) plays a critical role in osteoarthritis (OA) pathogenesis. This study investigates the role of the m6A reader insulin‐like growth factor 2 mRNA‐binding protein 3 (IGF2BP3) in OA progression. OA models were established in vivo through destabilization of the medial meniscus (DMM) surgery in mice and in vitro by ...
Xing‐Shi Yuan, Hao‐Jie Zhang, Jia‐Xiang Ding, Zheng‐Liang Luo, Min Chen, Xiao‐Qi Zhang, Xi‐Fu Shang, Zhe Ni, Ke‐Rong Wu   +8 more
wiley   +1 more source

B Cell Activation, Differentiation, and Their Potential Molecular Mechanisms in Osteoarthritic Synovial Tissue. [PDF]

J Inflamm Res
Lu P, Li Y, Yang S, Yao H, Tu B, Ning R.
europepmc   +1 more source

Disulfidptosis‐ and Ferroptosis‐Related Gene Signatures in Rheumatoid Arthritis: Association Analysis and Diagnostic Model Construction

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation and progressive joint damage. Although ferroptosis has been implicated in RA progression, the role of disulfidptosis and its interaction with ferroptosis remains unclear.
Ting‐Ting Wang, Dong‐Mei Wang, Xue Li, Yuan‐Li Wei, Ping‐Dan Liu, Shi‐Lin Li, Si‐Ying Xiong, Cai‐Zhen Liu, Fan‐Xin Zeng, Jian‐Hong Wu, Lin Tang   +10 more
wiley   +1 more source

Serum biochemical marker of synovial tissue turnover, C1M, predicts radiological progression in early rheumatoid arthritis. [PDF]

RMD Open
Garnero P, Falkenløve Madsen S, Eymard F, Sellam J, Chapurlat R, Bay-Jensen AC.   +5 more
europepmc   +1 more source

Autologous minimally manipulated adipose‐derived stromal vascular fraction in knee osteoarthritis: Lasting symptom relief and imaging evidence from a 12‐month prospective study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the safety and efficacy of intra‐articular autologous transplantation of adipose‐derived connective tissue micrografts rich in stromal vascular fraction (CTM‐SVF), obtained using an enzyme‐free system (Hy‐Tissue® SVF) for knee osteoarthritis (OA). Methods Thirty patients (mean age of 53.3 ± 6.4 years) with Kellgren–Lawrence
Laura Mangiavini, Nicolò Rossi, Riccardo Giorgino, Francesco Borelli, Alessandra Colombini, Paola De Luca, Simona Landoni, Luca Maria Sconfienza, Carmelo Messina, Irene Beriotto, Giuseppe M. Peretti, Laura de Girolamo   +11 more
wiley   +1 more source

VEGFA, MYC, and JUN are abnormally elevated in the synovial tissue of patients with advanced osteoarthritis. [PDF]

Sci Rep
Rong G, Zhang Z, Zhan W, Chen M, Ruan J, Shen C.   +5 more
europepmc   +1 more source

Impact of tear morphology and meniscal laterality on repair failure in stable knees: Medial repairs show over twofold risk

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the failure rates of all‐inside meniscal repair based on tear morphology in stable knees (i.e., without concomitant anterior cruciate ligament reconstruction [ACLR]) and to assess the influence of failure. Methods This retrospective cohort study included 1008 patients who underwent arthroscopic all‐inside meniscal repair ...
Christoffer von Essen, Riccardo Cristiani, Dzan Rizvanovic, Anders Stålman   +3 more
wiley   +1 more source

Constructing a 3D co-culture in vitro synovial tissue model for rheumatoid arthritis research. [PDF]

Mater Today Bio
Wang X, He J, Zhang Q, He J, Wang Q.
europepmc   +1 more source

Gait alterations increase friction of degenerated articular cartilage: A tribological study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To investigate the effect of gait alterations associated with osteoarthritis (OA) on the frictional properties of porcine articular cartilage (AC) in intact and degenerative conditions. Methods Forty‐eight cylindrical AC samples were harvested from 12 porcine femur condyles and equally divided between four groups with n = 12 samples ...
Luisa de Roy, Graciosa Quelhas Teixeira, Maria Ahrens, Benjamin Mayer, Cornelia Horsch, Anita Ignatius, Andreas Martin Seitz   +6 more
wiley   +1 more source