Results 111 to 120 of about 58,561 (288)

Impact of tear morphology and meniscal laterality on repair failure in stable knees: Medial repairs show over twofold risk

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the failure rates of all‐inside meniscal repair based on tear morphology in stable knees (i.e., without concomitant anterior cruciate ligament reconstruction [ACLR]) and to assess the influence of failure. Methods This retrospective cohort study included 1008 patients who underwent arthroscopic all‐inside meniscal repair ...
Christoffer von Essen, Riccardo Cristiani, Dzan Rizvanovic, Anders Stålman   +3 more
wiley   +1 more source

Long-term study of the impact of methotrexate on serum cytokines and lymphocyte subsets in patients with active rheumatoid arthritis: correlation with pharmacokinetic measures [PDF]

, 2016
Objective To describe changes in immune parameters observed during long-term methotrexate (MTX) therapy in patients with active rheumatoid arthritis (RA) and explore correlations with simultaneously measured MTX pharmacokinetic (PKC) parameters ...
Hamilton, Robert, Kremer, Joel M., Lawrence, David A., McInnes, Iain B.   +3 more
core   +1 more source

Managing the meniscus Part 2: Traumatic tear patterns, biologic augmentation, transplantation, innovation and future research

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Acute, traumatic meniscus tears are common and should be repaired whenever possible. However, the biological age of the patient, along with the specific tear morphology, may significantly influence the selection of the repair technique, expected clinical outcomes and the postoperative rehabilitation protocol.
Armin Runer, Matthew P. Kolevar, Ehab M. Nazzal, Jonathan D. Hughes, Sebastian Kopf, Aaron J. Krych, Michael T. Hirschmann, Robert F. LaPrade, Alan Getgood, Tim Spalding, Robert Prill, Maria Tuca, Matthieu Ollivier, Sebastian Siebenlist, Sachin Tapasvi, Volker Musahl   +15 more
wiley   +1 more source

The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17–producing cellular network at multiple sites [PDF]

, 2012
Among many survival strategies, parasitic worms secrete molecules to modulate host immune responses. One such product, ES-62, is protective in the collagen-induced arthritis (CIA) model of rheumatoid arthritis.
Al-Riyami, Benderdour, Chu, Collins, Conti, Cooke, Fang, Feng, Goodridge, Goodridge, Goodridge, Gulen, Harnett, Harrington, Ito, Ivanov, Kelchtermans, Kenny, Koenders, Koshy, Kulkarni, Langrish, Lubberts, Marshall, Martin, McInnes, Murugaiyan, Nakae, Naor, Niedbala, Petermann, Pickens, Price, Reynolds, Roark, Sato, Shahrara, Shibata, Staschke, Sutton, Szanto, Takayanagi, Tanaka, Vermeire, Whelan, Xu, Xu, Yago   +47 more
core   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Innervation of the synovium. [PDF]

Annals of the Rheumatic Diseases, 1995
This review will describe the normal innervation of the joints, in particular the synovium, and then show how this changes in the rheumatoid arthritis (RA) joint in the human. Substance P will be described in detail, as an example of a particular neuropeptide.
openaire   +2 more sources

Association of autoimmune diseases with biologic agents targeting type 2 immunity: An observational study using a claims database

Rheumatology &Autoimmunity, EarlyView.
This observational study assessed the association between anti‐type 2 biologic agents and the occurrence of autoimmune diseases using a large real‐world claims database. Anti‐IL‐5 and anti‐IgE therapies were associated with an increased occurrence of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Shoichiro Inokuchi
wiley   +1 more source

Successful repair of a carpal sheath synovial hernia using a polypropylene mesh

Equine Veterinary Education, EarlyView.
Summary A cob‐cross mare presented with a carpal sheath synovial hernia on the distolateral antebrachium following carpal sheath tenoscopy to treat a radial physeal exostosis and deep digital flexor tendon injury. The presumed source of pain was the weakened skin over the hernia as the intrathecal pathology identified at the initial tenoscopy had ...
S. R. L. Neild, J. D. Stack, M. D. Cullen, B. M. Curnow   +3 more
wiley   +1 more source

Increased FcγRII and III expression in synovium and on monocyte derived macrophages of RA-patients results in altered function after immune complex stimulation [PDF]

, 2002
A. Blom, P. van Lent, TRDJ Radstake, AEM Holthuysen, AW Slöetjes, RL Smeets, Pilar Barrera, LAB Joosten, WB van den Berg   +8 more
openalex   +1 more source

Needle tenoscopy of the digital flexor tendon sheath in four horses

Equine Veterinary Education, EarlyView.
Summary Background Tenoscopy, performed under general anaesthesia (GA), remains the gold standard diagnostic modality for assessment of the digital flexor tendon sheath (DFTS). A cadaver study described needle tenoscopy of the DFTS in a standing horse model, but the procedure has not been reported in clinical cases.
L. J. Breen, C. M. Baldwin, J. R. Vos, A. M. Gillen, J. D. Stack   +4 more
wiley   +1 more source