Results 91 to 100 of about 12,982,812 (373)
Communications Chemistry is pleased to introduce a Collection of research works focused on recent developments within the interdisciplinary field of chemoenzymatic synthesis. Here, the Guest Editors highlight key themes and look towards the future of this research field.
Borowiecki, Paweł, Schmidt, Sandy
openaire +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
EXTEND-L : an input language for extensible register transfer compilation [PDF]
This report discusses the model and input language for EXTEND, a synthesis system that permits extensible register transfer synthesis. EXTEND-L fills the need for a language that bridges the gap between existing behavioral input descriptions, which are ...
Dutt, Nikil D., Gajski, Daniel D.
core
In materials science, “green” synthesis has gained extensive attention as a reliable, sustainable, and eco-friendly protocol for synthesizing a wide range of materials/nanomaterials including metal/metal oxides nanomaterials, hybrid materials, and ...
Jagpreet Singh +5 more
semanticscholar +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Palladium-catalysed formation of vicinal all-carbon quaternary centres via propargylation
Formation of vicinal, quaternary stereocentres is challenging, but such products are commonly encountered in nature. Here, the authors report a palladium catalysed process to form vicinal quaternary carbons via propargylation, including in enantiopure ...
Xin Huang +5 more
doaj +1 more source
Optimization of Reaction Conditions in the Production of Gadolinium Diethylenetriamine Pentaacetate-Folate [PDF]
A previous study has performed the laboratory-scale synthesis and characterization of Gadolinium Diethylenetriaminepentaacetate-Folate. Some parameters associated with the synthesis have been defined.
Anggraeni, A. +3 more
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Cellophane-Based Membranes for Purification of Aqueous Media from Various Pollutants
The process of nanofiltration purification of water from various organic pollutants was examined. Cellophane film made from cheap natural raw materials was used as a membrane.
A. A. Yushkin +5 more
doaj +1 more source

