Results 171 to 180 of about 12,982,812 (373)

Guidelines for Synthesis and Processing of Two-Dimensional Titanium Carbide (Ti3C2Tx MXene)

, 2017
Mohamed Alhabeb, K. Maleski, B. Anasori, Pavel Lelyukh, L. Clark, Saleesha Sin, Y. Gogotsi   +6 more
semanticscholar   +1 more source

Switchable Synthesis of Aldehydes and Carboxylic Acids from Alcohols by Platinum‐Catalysed Hydrogen Peroxide Oxidation Using Flow Reactors [PDF]

, 2022
Yoshihiro Kon, Takuya Nakashima, Shun‐ya Onozawa, Kazuhiko Sato, Shu̅ Kobayashi   +4 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Use of pyridinium ionic liquids as catalysts for the synthesis of 3,5-bis(dodecyloxycarbonyl)-1,4-dihydropyridine derivative

Open Chemistry, 2011
Pajuste Karlis, Plotniece Aiva, Kore Kintija, Intenberga Liva, Cekavicus Brigita, Kaldre Dainis, Duburs Gunars, Sobolev Arkadij   +7 more
doaj   +1 more source

Discovery and molecular docking studies of nitrogen containing naphthyridine derivatives as potent HIV1 NNRTIs with anticancer potential

Scientific Reports
Fourteen novel 2,4-disubstituted-1,6- and 1,7-naphthyridine derivatives were developed to enhance HIV-1 RT inhibition through molecular hybridization of NNRTIs.
Apisara Baicharoen, Pongsit Vijitphan, Suwicha Patnin, Nanthawan Reukngam, Panita Khlaychan, Mayuso Kuno, Apinya Chaivisuthangkura, Supanna Techasakul, Arthit Makarasen   +8 more
doaj   +1 more source

Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs–CAIs) for the Treatment of Rheumatoid Arthritis

, 2017
Silvia Bua, Lorenzo Di Cesare Mannelli, Daniela Vullo, Carla Ghelardini, Gianluca Bartolucci, Andrea Scozzafava, Claudiu T. Supuran, Fabrizio Carta   +7 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver.

Journal of Clinical Investigation, 2002
J. Horton, J. Goldstein, Michael S. Brown   +2 more
semanticscholar   +1 more source

Solution synthesis of two-dimensional zinc oxide (ZnO)/molybdenum disulfide (MoS2) heterostructure through reactive templating for enhanced visible-light degradation of rhodamine B

, 2023
Lili Liu, Ping Chen, Xin Zhang, Libor Kovařík, James J. De Yoreo, Jun Liu, Maria L. Sushko   +6 more
openalex   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source