Results 171 to 180 of about 12,303,072 (355)

Grewiifopenes A–K, bioactive clerodane diterpenoids from Casearia grewiifolia Vent.

open access: yesNatural Products and Bioprospecting
Eleven novel clerodane-type diterpenoids, grewiifopenes A–K (1–4 and 12–18), along with nine known compounds (5–11, 19, and 20) were purified from the dichloromethane extract of the twigs and stems of Casearia grewiifolia Vent. (Salicaceae).
Phanruethai Pailee   +10 more
doaj   +1 more source

THE ENZYMATIC SYNTHESIS OF PHOSPHOPYRUVATE FROM PYRUVATE

open access: hybrid, 1945
Henry A. Lardy, John A. Ziegler
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Dehydroxylative radical N-glycosylation of heterocycles with 1-hydroxycarbohydrates enabled by copper metallaphotoredox catalysis

open access: yesNature Communications
N-Glycosylated heterocycles play important roles in biological systems and drug development. The synthesis of these compounds heavily relies on ionic N-glycosylation, which is usually constrained by factors such as labile glycosyl donors, precious metal ...
Da-Peng Liu   +3 more
doaj   +1 more source

EVIDENCE INDICATING A SYNTHESIS OF CHOLESTEROL BY INFANTS

open access: hybrid, 1920
James L. Gamble, Kenneth D. Blackfan
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

RÔLE OF ADENOSINETRIPHOSPHATE IN THE ENZYMATIC SYNTHESIS OF PHENYL SULFATE

open access: hybrid, 1953
R.H. De Meio   +2 more
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

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