Results 21 to 30 of about 343,223 (265)

Students’ conceptual performance on synthesis physics problems with varying mathematical complexity

open access: yesPhysical Review Physics Education Research, 2017
A body of research on physics problem solving has focused on single-concept problems. In this study we use “synthesis problems” that involve multiple concepts typically taught in different chapters.
Bashirah Ibrahim   +4 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Synthesis of a mobile robot spatial stabilization system based on machine learning control by symbolic regression

open access: yesRUDN Journal of Engineering Research, 2021
The spatial stabilization system synthesis problem of the robot is considered. The historical overview of methods and approaches for solving the problem of control synthesis is given.
Askhat I. Diveev   +1 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Adaptive wireless network multi-objective optimization algorithm based on image synthesis

open access: yesEURASIP Journal on Image and Video Processing, 2018
Multi-objective optimization problems can be divided into continuous multi-objective optimization problems and discrete multi-objective optimization problems, and discrete multi-objective optimization is not universal.
Jianwei Zhang, Xueya Zhang
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Optimum Path Synthesis of a Geared Five-Bar Mechanism

open access: yesAdvances in Mechanical Engineering, 2013
Most studies on path synthesis problems are to trace simple or smooth trajectories. In this work, an optimum synthesis for several special trajectories generated by a geared five-bar mechanism is studied using the one-phase synthesis method.
Wen-Yi Lin
doaj   +1 more source

A High-Level LTL Synthesis Format: TLSF v1.1 [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2016
We present the Temporal Logic Synthesis Format (TLSF), a high-level format to describe synthesis problems via Linear Temporal Logic (LTL). The format builds upon standard LTL, but additionally allows to use high-level constructs, such as sets and ...
Swen Jacobs   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy