Results 101 to 110 of about 2,952,613 (401)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A noncanonical role of roX RNAs in autosomal epigenetic repression

open access: yesNature Communications
Long noncoding RNAs known as roX (RNA on the X) are crucial for male development in Drosophila, as their loss leads to male lethality from the late larval stages.
Jianjian Li   +16 more
doaj   +1 more source

Harnessing bioengineered microbes as a versatile platform for space nutrition

open access: yesNature Communications, 2022
Long-duration human space travel creates challenges for maintaining healthy diets. Here the authors discuss using synthetic biology approaches to modify yeast into an optimal, and enjoyable, food production platform.
Briardo Llorente   +4 more
doaj   +1 more source

Design and Analysis of Genetically Constructed Logic Gates [PDF]

open access: yes, 2014
Synthetic biology, comprising many aspects including in vivo, in vitro and in silico techniques, models and methods, programming paradigms and tools, is a rapidly growing field with promising potential in building new synthetically constructed devices ...
Gheorghe, M., Konur, S.
core   +1 more source

Synthetic biology, inspired by synthetic chemistry

open access: yesFEBS Letters, 2012
We like to give an overview about the developments in the field of synthetic biology, regarding polymer‐based analogs of cellular membranes and what questions can be answered by applying synthetic polymer science towards the smallest unit in life, namely a cell.
Malinova, V.   +3 more
openaire   +3 more sources

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

A transient mutational burst occurs during yeast colony development

open access: yesMolecular Systems Biology
Characterizing the contribution of mutators to mutation accumulation is essential for understanding cellular adaptation and diseases like cancer. By measuring single and double mutation rates, including point mutations, segmental duplications, and ...
Nicolas Agier   +8 more
doaj   +1 more source

Machine learning approaches to predict the Plant-associated phenotype of Xanthomonas strains

open access: yesBMC Genomics, 2021
Background The genus Xanthomonas has long been considered to consist predominantly of plant pathogens, but over the last decade there has been an increasing number of reports on non-pathogenic and endophytic members.
Dennie te Molder   +3 more
doaj   +1 more source

Bayesian and Algebraic Strategies to Design in Synthetic Biology [PDF]

open access: green, 2021
Robyn P. Araujo   +2 more
openalex   +1 more source

Making serine integrases work for us [PDF]

open access: yes, 2017
DNA site-specific recombinases are enzymes (often associated with mobile DNA elements) that catalyse breaking and rejoining of DNA strands at specific points, thereby bringing about precise genetic rearrangements.
Stark, W. Marshall
core   +1 more source

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