Results 181 to 190 of about 435,061 (337)

Mathematical Modeling: Bridging the Gap between Concept and Realization in Synthetic Biology [PDF]

, 2010
Yuting Zheng, Ganesh Sriram
openalex   +1 more source

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

BAC-browser: the tool for synthetic biology. [PDF]

BMC Bioinformatics
Semashko TA, Fisunov GY, Shevelev GY, Govorun VM.   +3 more
europepmc   +1 more source

Tales of Emergence—Synthetic Biology as a Scientific Community in the Making

, 2009
Susan Molyneux‐Hodgson, Morgan Meyer
openalex   +2 more sources

Engineering of a genome-reduced host: practical application of synthetic biology in the overproduction of desired secondary metabolites [PDF]

, 2010
Hong Gao, Ying Zhuo, Elizabeth Jane Ashforth, Lixin Zhang   +3 more
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Synthetic biology routes to new and extinct natural products. [PDF]

RSC Chem Biol
Simpson TJ.
europepmc   +1 more source

The impact of synthetic biology on drug discovery

, 2009
Wilfried Weber, Martin Fussenegger
openalex   +1 more source

Patentability of synthetic biology inventions in Europe [PDF]

, 2010
Berthold Rutz
openalex   +1 more source

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

FEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang, Kaien Hu, Zhaohui Fang, Sihai Wang, Jie Chen, Dengke Yin, Caiyun Zhang, Gefei Ma   +7 more
wiley   +1 more source