Results 211 to 220 of about 1,044,094 (254)
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Blood concentrations of synthetic cannabinoids
Clinical Toxicology, 2020Synthetic cannabinoids (SCs) are the largest and most diverse group of new psychoactive substances. Their influence on organism is unpredictable and often lead to intoxications, including fatal poisonings. The interpretation of blood concentrations of detected SC although complicated, can help to determine the effects of an administered drug.
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Journal of Psychiatric Practice, 2012
In the past few years, synthetic cannabinoid products have been increasingly used by adolescents and young adults. These products are marketed as herbal or aromatic incense and potpourri, but their psychoactive properties appear to be due to the addition of synthetic cannabinoids.
Daniel, Castellanos, Gabriel, Thornton
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In the past few years, synthetic cannabinoid products have been increasingly used by adolescents and young adults. These products are marketed as herbal or aromatic incense and potpourri, but their psychoactive properties appear to be due to the addition of synthetic cannabinoids.
Daniel, Castellanos, Gabriel, Thornton
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The emergence and analysis of synthetic cannabinoids
Drug Testing and Analysis, 2011AbstractIn late 2008, several synthetic cannabinoids were detected in herbal smoking mixtures. Typical of these products were ‘Spice Gold’, ‘Spice Silver’ and ‘Yucatan Fire’, but many other products have since appeared. The analytes detected, such as JWH‐018 and CP47,497 are experimental compounds, some of which were never designed for human use.Both ...
Simon, Hudson, John, Ramsey
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The Synthetic Cannabinoid Withdrawal Syndrome
Journal of Addiction Medicine, 2013Little is known about the effects of synthetic cannabinoids. There has been only one previous report of a withdrawal syndrome from synthetic cannabinoids. We report two cases of a withdrawal syndrome from prolonged habitual use of synthetic cannabinoids.Withdrawal from delta-9-THC has been described as a syndrome of anxiety, myalgias, chills, and ...
Nicholas, Nacca +5 more
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Interpersonal violence and synthetic cannabinoids
British Journal of Oral and Maxillofacial Surgery, 2017The medicinal benefits of cannabis have led to the develpment of synthetic cannabinoid receptor agonists, for the alliation of cancer and other conditions.1 Unfortunately, llicit manufacturers have commandeered their production or recreational use. Known colloquially as “spice”, or by ther pseudonyms, these substances have garnered attention n the ...
Alexander J, Rickart +2 more
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Synthetic cannabinoids: Analysis and metabolites
Life Sciences, 2014Cannabimimetics (commonly referred to as synthetic cannabinoids), a group of compounds encompassing a wide range of chemical structures, have been developed by scientists with the hope of achieving selectivity toward one or the other of the cannabinoid receptors CB1 and CB2.
Mahmoud A. ElSohly +3 more
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Metabolism of classical cannabinoids and the synthetic cannabinoid JWH‐018
Clinical Pharmacology & Therapeutics, 2015Although the putative pharmacological targets of synthetic cannabinoids (SCBs) abused in “K2” and “Spice” are similar to Δ9‐tetrahydrocannabinol (Δ9‐THC), it remains unclear why SCB toxicity is similar yet different from marijuana. There are obvious potency and efficacy differences, but also important metabolic differences that help explain the unique ...
M K, Su +3 more
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Plant, Synthetic, and Endogenous Cannabinoids in Medicine
Annual Review of Medicine, 2006Although used for more than 4000 years for recreational and medicinal purposes, Cannabis and its best-known pharmacologically active constituents, the cannabinoids, became a protagonist in medical research only recently. This revival of interest is explained by the finding in the 1990s of the mechanism of action of the main psychotropic cannabinoid ...
Di Marzo V, De Petrocellis L
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Synthetic Cannabinoids as Drugs of Abuse
Current Drug Abuse Reviewse, 2012In the last decade a number of products have appeared in various countries that contain synthetic cannabinoids. This article reviews the history of the sale of these drugs, and the evidence that they contain synthetic cannabinoids. The biochemistry of the synthetic cannabinoids identified thus far is discussed, including a discussion of chemical ...
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