Results 71 to 80 of about 27,649 (256)

Synthetic cathinones related fatalities: an update [PDF]

open access: yes, 2018
Synthetic cathinones, more commonly known as "bath salts", are synthetic drugs chemically related to cathinone, a psychostimulant found in the khat plant.
Busardò, F. P.   +5 more
core   +1 more source

Gray Matter Volume Loss in Parkinson's Disease Psychosis and Cannabinoid Receptor Gene Expression in the Brain

open access: yesMovement Disorders, EarlyView.
Abstract Background Serotonergic and dopaminergic pathways are implicated in Parkinson's disease psychosis (PDP), but preliminary evidence also implicates the endocannabinoid system (ECS). Objectives We examined the association of gray matter volume loss in PDP patients with brain expression of the genes coding for CB1 (cannabinoid type 1) and CB2 ...
Sara Pisani   +3 more
wiley   +1 more source

Recreational use, analysis and toxicity of tryptamines [PDF]

open access: yes, 2015
The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs.
Mannocchi, Giulio   +3 more
core   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur   +6 more
wiley   +1 more source

Vaping Synthetic Cannabinoids: A Novel Preclinical Model of E-Cigarette Use in Mice

open access: yesSubstance Abuse: Research and Treatment, 2017
Smoking is the most common route of administration for cannabis; however, vaping cannabis extracts and synthetic cannabinoids (“fake marijuana”) in electronic cigarette devices has become increasingly popular.
Timothy W Lefever   +6 more
doaj   +1 more source

Handheld raman spectrometer for the rapid determination of synthetic cannabinoids

open access: yesJournal of Forensic Science and Medicine, 2019
A handheld laser Raman spectrometer was developed to detect 11 synthetic cannabinoid standards. The spectrometer can be connected with a mobile phone by Bluetooth or a computer by a data cable.
Ling Zhang, Guoping Li
doaj   +1 more source

Market Analysis of Plant-based Drugs C. The Cannabis Market [PDF]

open access: yes, 2017
An estimated quarter of a billion people, or around 5 per cent of the global adult population, used drugs at least once in 2015. Even more worrisome is the fact that about 29.5 million of those drug users, or 0.6 per cent of the global adult population ...

core  

Exploring the baseline knowledge and experience of healthcare professionals in the United Kingdom on Novel Psychoactive Substances [PDF]

open access: yes, 2020
Submitted 28 january 2020. Reviwers' comments received 11 February 2020. Accepted 26 February 2020. Published 2 March 2020.Objective: This survey aimed to explore knowledge and experience on novel psychoactive substances (NPS) of healthcare professionals
Bancroft, Angus   +9 more
core   +3 more sources

Exploring Linalool‐Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli   +4 more
wiley   +1 more source

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