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Synthetic Cathinones (“Bath Salts”) [PDF]

Journal of Emergency Medicine, 2014
Synthetic cathinones are popularly referred to in the media as "bath salts." Through the direct and indirect activation of the sympathetic nervous system, smoking, snorting, or injecting synthetic cathinones can result in tachycardia, hypertension, hyperthermia, myocardial infarction, and death.The chemical structures and names of bath salts identified
Matthew L Banks, Travis J Worst, Daniel E Rusyniak   +2 more
exaly   +3 more sources

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Synthetic cathinones and cardiotoxicity risks.

La Clinica terapeutica, 2022
Recently, there has been a worldwide rise in the popularity and abuse of synthetic cathinones. The spectrum of side effects caused by the intake of these drugs of abuse is very wide since they act on different systems with various mechanisms of action, they appear to be involved in different cardiac events, including myocardial infarction and sudden ...
Lo Faro, A., Berretta, P., Montana , A.
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An updated review on synthetic cathinones

Archives of Toxicology, 2021
Cathinone, the main psychoactive compound found in the plant Catha edulis Forsk. (khat), is a β-keto analogue of amphetamine, sharing not only the phenethylamine structure, but also the amphetamine-like stimulant effects. Synthetic cathinones are derivatives of the naturally occurring cathinone that largely entered the recreational drug market at the ...
Jorge Soares, Vera Marisa Costa, Maria de Lourdes Bastos, Félix Carvalho, João Paulo Capela   +4 more
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Stability of synthetic cathinones in blood and urine

Forensic Science International, 2019
Although there is an observed decline in the number of new psychoactive substances entering the drug market, this phenomenon is still a significant public health problem. Synthetic cathinones are the second largest group of new substances and currently belong to the most frequently confiscated.
Piotr Adamowicz
exaly   +4 more sources

Khat and synthetic cathinones: a review

Archives of Toxicology, 2013
For centuries, 'khat sessions' have played a key role in the social and cultural traditions among several communities around Saudi Arabia and most East African countries. The identification of cathinone as the main psychoactive compound of khat leaves, exhibiting amphetamine-like pharmacological properties, resulted in the synthesis of several ...
Valente, Maria João, Guedes de Pinho, Paula, de Lourdes Bastos, Maria, Carvalho, Félix, Carvalho, Márcia   +4 more
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Blood concentrations of synthetic cathinones

Clinical Toxicology, 2020
Synthetic cathinones are the second most frequently seized group of new psychoactive substances. They are sold as replacements for controlled stimulants such as amphetamine, cocaine and MDMA. Synthetic cathinones are often determined in biological material collected from both living people and fatally intoxicated with these substances.
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Synthetic cathinones: Chemical phylogeny, physiology, and neuropharmacology [PDF]

Life Sciences, 2014
This mini-review summarizes the history of cathinone and its synthesized derivatives from early records to the present day, including the appearance of synthetic cathinones in the drug combination known as bath salts. Bath salts may consist of one compound (MDPV) or combinations of MDPV and one or more other synthetic cathinones, which may also appear ...
Louis J de Felice, Richard A Glennon, S Stevens Negus   +2 more
exaly   +3 more sources

Synthetic cathinones: “A khat and mouse game”

Toxicology Letters, 2014
The birth of the twenty first century has provoked a substantial rise in the use of designer drugs, such as synthetic cathinones, because of a decrease in the availability and purity of other drugs of abuse. The khat plant or Catha edulis, contains cathinone, the parent compound.
Daniel P, Katz, Dwipayan, Bhattacharya, Subhrajit, Bhattacharya, Jack, Deruiter, C Randall, Clark, Vishnu, Suppiramaniam, Muralikrishnan, Dhanasekaran   +6 more
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Fragmentation pathways of α-pyrrolidinophenone synthetic cathinones and their application to the identification of emerging synthetic cathinone derivatives

International Journal of Mass Spectrometry, 2020
Abstract The expanding use of emerging synthetic drugs is creating a growing problem for both seized drug analysts and toxicologists because the clandestine suppliers continually tweak the chemical structures to keep one step ahead of the law. Synthetic cathinones, commonly referred to as bath salts, are a specific class of emerging synthetic drugs ...
J. Tyler Davidson, Zachary J. Sasiene, Younis Abiedalla, J. DeRuiter, C. Randall Clark, Glen P. Jackson   +5 more
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The pharmacology and neurotoxicology of synthetic cathinones

The synthetic cathinones are man-made compounds derived from the naturally occurring drug cathinone, which is found in the khat plant. The drugs in this pharmacological class that will be the focus of this chapter include mephedrone, MDPV, methcathinone and methylone. These drugs are colloquially known as "bath salts". This misnomer suggests that these
Mariana, Angoa-Perez, Donald M, Kuhn
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