Results 1 to 10 of about 24,901 (225)

A mechanistic overview of approaches for the treatment of psychostimulant dependence

open access: yesFrontiers in Pharmacology, 2022
Psychostimulant use disorder is a major health issue around the world with enormous individual, family-related and societal consequences, yet there are no effective pharmacological treatments available.
Kathrine L Jensen, Kenneth L Madsen
exaly   +3 more sources

Effectiveness of Psychostimulant and Non-Psychostimulant Drug Therapy in the Attention Deficit Hyperactivity Disorder

open access: yesApplied Sciences, 2021
Attention Deficit Hyperkinetic Disorder (ADHD) is a neurobiological behavioral disorder of the child, adolescent, and adult characterized by problems of concentration, hyperactivity, and impulsivity caused by an imbalance of chemical neurotransmitters in
Adriana Cojocaru   +13 more
doaj   +1 more source

Dopamine Neurons That Cotransmit Glutamate, From Synapses to Circuits to Behavior

open access: yesFrontiers in Neural Circuits, 2021
Discovered just over 20 years ago, dopamine neurons have the ability to cotransmit both dopamine and glutamate. Yet, the functional roles of dopamine neuron glutamate cotransmission and their implications for therapeutic use are just emerging.
Daniel Eskenazi   +16 more
doaj   +1 more source

Case Report: Treatment of a Comorbid Attention Deficit Hyperactivity Disorder and Obsessive–Compulsive Disorder With Psychostimulants

open access: yesFrontiers in Psychiatry, 2021
Introduction: Attention deficit hyperactivity disorder (ADHD) is a common disease in childhood and adolescence. In about 60% of pediatric patients, the symptoms persist into adulthood.
Ezgi Dogan-Sander, Maria Strauß
doaj   +1 more source

Structure–Activity Relationship of Novel Second-Generation Synthetic Cathinones: Mechanism of Action, Locomotion, Reward, and Immediate-Early Genes

open access: yesFrontiers in Pharmacology, 2021
Several new synthetic cathinones, which mimic the effect of classical psychostimulants such as cocaine or MDMA, have appeared in the global illicit drug market in the last decades.
Nuria Nadal-Gratacós   +16 more
doaj   +1 more source

The effect of caffeine, nap opportunity and their combination on biomarkers of muscle damage and antioxidant defence during repeated sprint exercise

open access: yesBiology of Sport, 2021
To investigate the effect of 20 min nap opportunity (N20), 5 mg · kg -1 of caffeine (CAF) and their combination (CAF+N20) on the biochemical response (energetic biomarkers, biomarkers of muscle damage and enzymatic antioxidants) to the running-based ...
Mohamed Romdhani   +9 more
doaj   +1 more source

Cellular Uptake of Psychostimulants – Are High- and Low-Affinity Organic Cation Transporters Drug Traffickers?

open access: yesFrontiers in Pharmacology, 2021
Psychostimulants are used therapeutically and for illegal recreational purposes. Many of these are inhibitors of the presynaptic noradrenaline, dopamine, and serotonin transporters (NET, DAT, and SERT). According to their physicochemical properties, some
Ole Jensen   +3 more
doaj   +1 more source

The Adverse Effects of Prenatal METH Exposure on the Offspring: A Review

open access: yesFrontiers in Pharmacology, 2021
Abuse of methamphetamine (METH), an illicit psychostimulant, is a growing public health issue. METH abuse during pregnancy is on the rise due to its stimulant, anorectic, and hallucinogenic properties.
Jia-Hao Li   +5 more
doaj   +1 more source

Concomitant medication use and clinical outcome of repetitive Transcranial Magnetic Stimulation (rTMS) treatment of Major Depressive Disorder. [PDF]

open access: yes, 2019
BackgroundRepetitive Transcranial Magnetic Stimulation (rTMS) is commonly administered to Major Depressive Disorder (MDD) patients taking psychotropic medications, yet the effects on treatment outcomes remain unknown.
Chawla, Shweta A   +7 more
core   +1 more source

Enkephalin as a Pivotal Player in Neuroadaptations Related to Psychostimulant Addiction

open access: yesFrontiers in Psychiatry, 2018
Enkephalin expression is high in mesocorticolimbic areas associated with psychostimulant-induced behavioral and neurobiological effects, and may also modulate local neurotransmission in this circuit network.
Bethania Mongi-Bragato   +4 more
doaj   +1 more source

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