Results 41 to 50 of about 24,901 (225)
Neurologic Clinics, 1993 Psychomotor stimulants possess intrinsic reinforcing properties that may lead to dependence and abuse. Epidemics of stimulant abuse have occurred historically in cycles related to introduction of new stimulants or new routes of administration. The actions and toxic effects of stimulants are related primarily to interaction with the central and ...
openaire +2 more sources
Tonic inhibition of accumbal spiny neurons by extrasynaptic 4 GABAA receptors modulates the actions of psychostimulants [PDF]
, 2014 Within the nucleus accumbens (NAc), synaptic GABAA receptors (GABAARs) mediate phasic inhibition of medium spiny neurons (MSNs) and influence behavioral responses to cocaine.
Belelli, D +8 more
core +1 more source
An examination of the effects of stimulant medication on response inhibition: A comparison between children with and without attention deficit hyperactivity disorder [PDF]
, 2011 This study investigated whether methylphenidate is effective in improving response inhibition in children with Attention Deficit Hyperactivity Disorder (ADHD).
Brackenridge, Rachel +3 more
core +1 more source
Prenatal and acute cocaine exposure affects neural responses and habituation to visual stimuli
Frontiers in Neural Circuits, 2015 Psychostimulants have many effects on visual function, from adverse, following acute and prenatal exposure to therapeutic, on attention deficit. To determine the impact of prenatal and acute cocaine exposure on visual processing, we studied neuronal ...
Elizabeth Brooke Riley +4 more
doaj +1 more source
BMC Emergency Medicine, 2022 Background Drug-related emergency department (ED) visits are escalating, especially for stimulant use (i.e., cocaine and psychostimulants such as methamphetamine).
Leslie W. Suen +4 more
doaj +1 more source
Cells, 2022 Plasma membrane monoamine transporter (PMAT, Slc29a4) transports monoamine neurotransmitters, including dopamine and serotonin, faster than more studied monoamine transporters, e.g., dopamine transporter (DAT), or serotonin transporter (SERT), but with ...
Jasmin N. Beaver +5 more
doaj +1 more source
Epilepsia, EarlyView.Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden +5 more
wiley +1 more source
Influence of acute caffeine on 50-kHz ultrasonic vocalizations in male adult rats and relevance to caffeine-mediated psychopharmacological effects [PDF]
, 2010 To further characterize caffeine-mediated psychopharmacological effects, the present study investigated whether acute caffeine (3, 10, 30, 50 mg/kg i.p.) exerted any influence on the emission and features of ultrasonic vocalizations (USVs), which are ...
Ma ST, Schallert, T, Simola, N
core +1 more source
Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome
Food Biomacromolecules, EarlyView.Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley +1 more source