Results 21 to 30 of about 24,901 (225)

Cocaine exposure shifts the balance of associative encoding from ventral to dorsolateral striatum

Frontiers in Integrative Neuroscience, 2007
Both dorsal and ventral striatum are implicated in the "habitization" of behavior that occurs in addiction. Here we examined the effect of cocaine exposure on associative encoding in these two regions.
Yuji Takahashi, Matthew R Roesch, Thomas A Stalnaker, Geoffrey Schoenbaum, Geoffrey Schoenbaum, Geoffrey Schoenbaum   +5 more
doaj   +1 more source

Entry in the ADHD drugs market: Welfare impact of generics and me-toos [PDF]

, 2013
Recent decades have seen a growth in treatments for attention deficit hyperactivity disorder (ADHD) including many branded and generic drugs. In the early 2000's, new drug entry dramatically altered market shares.
Angell M., Barkley R. A., Bulow J., Conner D. F., Deaton A., FDAnews Drug Daily Bulletin, Frank R. G., Goozner M., Hausman J. A., Hausman J. A., Perwien A. R., Rector T. S., Safer D. J., Shulman S. R., Spencer T. J.   +14 more
core   +1 more source

Widespread increases in malondialdehyde immunoreactivity in dopamine-rich and dopamine-poor regions of rat brain following multiple, high doses of methamphetamine.

Frontiers in Systems Neuroscience, 2011
Treatment with multiple high doses of methamphetamine (METH) can induce oxidative damage, including dopamine (DA)-mediated reactive oxygen species (ROS) formation, which may contribute to the neurotoxic damage of monoamine neurons and long-term depletion
Kristen Ashley eHorner, Yamiece E. Gilbert, Susan D. Cline   +2 more
doaj   +1 more source

Leptin Protects Against the Development and Expression of Cocaine Addiction-Like Behavior in Heterogeneous Stock Rats

Frontiers in Behavioral Neuroscience, 2022
Cocaine affects food intake, metabolism and bodyweight. It has been hypothesized that feeding hormones like leptin play a role in this process. Preclinical studies have shown a mutually inhibitory relationship between leptin and cocaine, with leptin also
Lieselot L. G. Carrette, Cristina Corral, Brent Boomhower, Molly Brennan, Caitlin Crook, Clara Ortez, Kokila Shankar, Kokila Shankar, Sierra Simpson, Lisa Maturin, Leah C. Solberg Woods, Abraham A. Palmer, Abraham A. Palmer, Giordano de Guglielmo, Olivier George   +14 more
doaj   +1 more source

Conditioned place preference and locomotor activity in response to methylphenidate, amphetamine and cocaine in mice lacking dopamine D4 receptors [PDF]

, 2010
Methylphenidate (MP) and amphetamine (AMPH) are the most frequently prescribed medications for the treatment of attention-deficit/hyperactivity disorder (ADHD).
Bermeo, C., Grandy, David K., Rubinstein, Marcelo, Suchland, K. L., Thanos, P. K., Volkow, N. D., Wang, G. J.   +6 more
core   +1 more source

From ABCs to ADHD: the role of schooling in the construction of behaviour disorder and production of disorderly objects [PDF]

, 2008
Discussion of Attention-Deficit/Hyperactivity Disorder (ADHD) in the media, and thus much popular discourse, typically revolves around the possible causes of disruptive behaviour and the “behaviourally disordered” child.
Graham, Linda
core   +2 more sources

Psychostimulants As Cognitive Enhancers in Adolescents: More Risk than Reward?

Frontiers in Public Health, 2017
Methylphenidate and other psychostimulants, originally developed to treat attention deficit-hyperactivity disorder, are increasingly abused by healthy adolescents and adults seeking an advantage in scholastic performance and work productivity.
Kimberly R. Urban, Wen-Jun Gao
doaj   +1 more source

Brain iron levels in attention-deficit/hyperactivity disorder normalize as a function of psychostimulant treatment duration

NeuroImage: Clinical, 2019
Brain iron homeostasis is a dopamine-related mechanism that may be modified with long-term psychostimulant treatment in attention-deficit/hyperactivity disorder (ADHD). We previously reported that while medication-naïve youth with ADHD have reduced brain
Vitria Adisetiyo, Kevin M. Gray, Jens H. Jensen, Joseph A. Helpern   +3 more
doaj   +1 more source

Synthetic cathinones related fatalities: an update [PDF]

, 2018
Synthetic cathinones, more commonly known as "bath salts", are synthetic drugs chemically related to cathinone, a psychostimulant found in the khat plant.
Busardò, F. P., Giorgetti, R., Marinelli, E., Pantano, F., Pichini, S., Zaami, S.   +5 more
core   +1 more source

Treatment of ADHD: Guanfacine Extended Release in ADHD

Pediatric Neurology Briefs, 2014
Investigators at Massachusetts General Hospital, Boston, MA, performed a multicenter, 9-week, double-blind, placebo-controlled, dose-optimization study of guanfacine extended release (GXR,
J Gordon Millichap, John J Millichap
doaj   +1 more source