Results 31 to 40 of about 24,901 (225)

The role of setting for ketamine abuse: clinical and preclinical evidence [PDF]

open access: yes, 2012
Drug abuse is often seen as a unitary phenomenon, partly as a result of the discovery over the past three decades of shared mechanisms of action for addictive substances. Yet the pattern of drug taking is often very different from drug to drug.
Sprenger   +8 more
core   +1 more source

Reinforcing Effects of the Synthetic Cathinone α-Pyrrolidinopropiophenone (α-PPP) in a Repeated Extended Access Binge Paradigm

open access: yesFrontiers in Psychiatry, 2020
Synthetic cathinones are designer psychostimulants that are derivatives of the natural alkaloid cathinone, and produce effects similar to more traditional illicit stimulants such as cocaine and methamphetamine.
Erin K. Nagy   +2 more
doaj   +1 more source

Association between Individual Norepinephrine Transporter (NET) Availability and Response to Pharmacological Therapy in Adults with Attention-Deficit/Hyperactivity Disorder (ADHD)

open access: yesBrain Sciences, 2022
Background: The role of the norepinephrine transporter (NET) has received increased focus in recent studies on the pathogenesis of attention-deficit/hyperactivity disorder (ADHD).
Jue Huang   +9 more
doaj   +1 more source

Neurotoxicity induced by mephedrone: an up-to-date review [PDF]

open access: yes, 2017
BACKGROUND: Mephedrone is a β-ketoamphetamine belonging to the family of synthetic cathinones, an emerging class of designer drugs known for their hallucinogenic and psychostimulant properties as well as for their abuse potential.
Busardo', FRANCESCO PAOLO   +6 more
core   +1 more source

Hippocampal BDNF regulates a shift from flexible, goal-directed to habit memory system function following cocaine abstinence. [PDF]

open access: yes, 2019
The transition from recreational drug use to addiction involves pathological learning processes that support a persistent shift from flexible, goal-directed to habit behavioral control.
Blurton-Jones, Matthew   +2 more
core   +1 more source

Role of Cannabidiol in the Therapeutic Intervention for Substance Use Disorders

open access: yesFrontiers in Pharmacology, 2021
Drug treatments available for the management of substance use disorders (SUD) present multiple limitations in efficacy, lack of approved treatments or alarming relapse rates. These facts hamper the clinical outcome and the quality of life of the patients
Francisco Navarrete   +8 more
doaj   +1 more source

Modeling neurocognitive and neurobiological recovery in addiction [PDF]

open access: yes, 2019
This book focuses on "what to know" and "how to apply" information, prioritizing novel principles and delineating cutting-edge assessment, phenotyping and treatment ...
Abé   +179 more
core   +1 more source

Modafinil-Induced changes in functional connectivity in the cortex and cerebellum of healthy elderly subjects [PDF]

open access: yes, 2017
In the past few years, cognitive enhancing drugs (CEDs) have gained growing interest and the focus of investigations aimed at exploring their use to potentiate the cognitive performances of healthy individuals.
Caltagirone, Carlo   +6 more
core   +3 more sources

Roar of meow-meow (mephedrone) in India

open access: yesJournal of Mental Health and Human Behaviour, 2015
Recently, a dangerous new designer drug mephedrone has fast gained popularity among the youth and teens of India. Its abuse has soared to mount to an epidemic.
Pooja Yudhishthir Palkar   +1 more
doaj   +1 more source

Methylphenidate treatment beyond adolescence maintains increased cocaine self-administration in the spontaneously hypertensive rat model of attention deficit/hyperactivity disorder [PDF]

open access: yes, 2015
Past research with the spontaneously hypertensive rat (SHR) model of attention deficit/hyperactivity disorder showed that adolescent methylphenidate treatment enhanced cocaine abuse risk in SHR during adulthood.
Baskin, Britahny M.   +2 more
core   +1 more source

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