Results 41 to 50 of about 4,485 (207)

SODAS: Surveillance of Drugs of Abuse Study [PDF]

, 2017
Objective: Novel Psychoactive Substance (NPS) as a form of recreational drug use has become increasingly popular. There is a paucity of information with regards the prevalence and clinical sequalae of these drugs.
Bloeck, Felix, Ireland, Alastair, Lowe, David J., Stevenson, Richard, Torrance, Hazel   +4 more
core   +1 more source

DFT calculations as an efficient tool for prediction of Raman and infra-red spectra and activities of newly synthesized cathinones

Open Chemistry, 2020
Initially made for medical treatment for Parkinsonism, obesity, and depression, cathinones have become illegal drugs for the “recreational use”. The mechanism of action of synthetic cathinones consists of the inhibition of monoamine transporters.
Vujović Maja, Ragavendran Venkatesan, Arsić Biljana, Kostić Emilija, Mladenović Milan   +4 more
doaj   +1 more source

4-Isobutylmethcathinone—A Novel Synthetic Cathinone with High In Vitro Cytotoxicity and Strong Receptor Binding Preference of Enantiomers

Pharmaceuticals, 2022
New psychoactive substances and among them synthetic cathinones represent a significant threat to human health globally. However, within such a large pool of substances derived from a natural compound ((S)-cathinone), substances with important ...
Martin Paškan, Silvie Rimpelová, Vladimíra Svobodová Pavlíčková, Dita Spálovská, Vladimír Setnička, Martin Kuchař, Michal Kohout   +6 more
doaj   +1 more source

Toxicokinetics of the Synthetic Cathinone α-Pyrrolidinohexanophenone [PDF]

Journal of Analytical Toxicology, 2017
Synthetic cathinones inhibit monoamine transporters, such as serotonin, norepinephrine, and dopamine transporters, and act on the central nervous system via increasing synaptic concentrations of monoamines. These compounds, which are highly addictive and potentially poisonous, are new psychoactive substances.
Yuji, Fujita, Toshinori, Mita, Kiyotaka, Usui, Yoshito, Kamijo, Satoshi, Kikuchi, Makoto, Onodera, Yasuhisa, Fujino, Yoshihiro, Inoue   +7 more
openaire   +2 more sources

Detecting a signal in the noise : Monitoring the global spread of novel psychoactive substances using media and other open source information [PDF]

, 2015
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no ...
Canadian Community Epidemiology Network On Drug Use, Center for Substance Abuse Research, European Monitoring Centre For Drugs And Drug Addiction, Sumnall H   +3 more
core   +1 more source

Synthetic cannabinoid use in a case series of patients with psychosis presenting to acute psychiatric settings : Clinical presentation and management issues [PDF]

, 2018
Background: Novel Psychoactive Substances (NPS) are a heterogeneous class of synthetic molecules including synthetic cannabinoid receptor agonists (SCRAs). Psychosis is associated with SCRAs use.
Bonaccorso, Stefania, Ducci, Giuseppe, Ferracuti, Stefano, Jamal, Leila, Metastasio, Antonio, Ricciardi, Angelo, Rujully, Naasir Ud Dinn, Schifano, Fabrizio, Stewart, Neil, Theleritis, Christos   +9 more
core   +3 more sources

Synthetic cathinone adulteration of illegal drugs [PDF]

Psychopharmacology, 2018
Current prevalence estimates of synthetic cathinone ("bath salt") use may be underestimates given that traditional metrics (e.g., surveys, urinalysis) often fail to capture the emergent issue of synthetic cathinone adulteration of more common illegal drugs, such as ecstasy (3,4-methylenedioxymethamphetamine).This review examines the evolution of ...
Oliver CF, Palamar JJ, Salomone A, Simmons SJ, Philogene-Khalid HL, Stokes-McCloskey N, Rawls SM.   +6 more
openaire   +3 more sources

Novel Psychoactive Substances: : the pharmacology of stimulants and hallucinogens [PDF]

, 2016
This is an Accepted Manuscript of an article published by Taylor & Francis in Expert Review of Clinical Pharmacology, on March 2016, available online at doi: : http://www.tandfonline.com/doi/full/10.1586/17512433.2016.1167597.There are increasing levels ...
Corkery JM, Daly M, Dargan PI, Fabrizio Schifano, Farrè M, G. Duccio Papanti, John M. Corkery, Laura Orsolini, Shulgin AT, Shulgin AT, Soussan C, Ujváry I   +11 more
core   +3 more sources

The effects and toxicity of cathinones from the users' perspectives: A qualitative study. [PDF]

, 2017
OBJECTIVE: The objective of this study is to explore the users' perspectives regarding the effects and toxicity of cathinones. METHODS: A systematic search of Internet discussion forums yielded 303 threads relevant to the research objectives. The threads
Assi, Sulaf, Gulyamova, N., Kneller, Paul, Osselton, David M.   +3 more
core   +2 more sources

Extraction of synthetic cathinones from biological samples: A systematic review

Advances in Sample Preparation
Analysis of biological samples containing synthetic cathinones has become a significant area of interest for researchers in recent years, because synthetic cathinones can cause adverse reactions such as delusions and hallucinations.
Mengjie Gu, Shutong Xue, Menghan Hou, Xiantao Shen   +3 more
doaj   +1 more source