Results 71 to 80 of about 4,485 (207)

Synthetic Cathinones and Their Potential Interactions with Prescription Drugs

open access: yesTherapeutic Drug Monitoring, 2020
Purpose: Substance use disorder often coexists with other psychiatric disorders, resulting in the simultaneous use of recreational and prescription drugs. The authors aimed to identify potential pharmacokinetic and pharmacodynamic interactions between new psychoactive substances of the cathinone class and specific prescription ...
Contrucci, R.R.   +4 more
openaire   +3 more sources

New screening and quantification method by UHPLC-MS/MS of 36 new synthetic cathinones in hair. Application to real cases

open access: yesJournal of Pharmaceutical and Biomedical Analysis Open
A class of β-keto analogs of phenethylamine known as synthetic cathinones has been identified as the most emergent new class of psychoactive chemicals in the last ten years.
Alfredo Fabrizio Lo Faro   +7 more
doaj   +1 more source

Extended Stability Evaluation of Selected Cathinones

open access: yesFrontiers in Chemistry, 2020
Understanding the stability of drugs in a forensic toxicology setting is critical for the evaluation of drug concentrations. Synthetic cathinones are new psychoactive substances structurally derived from cathinone, the psychoactive component of Catha ...
Heather L. Ciallella   +3 more
doaj   +1 more source

Effects of Serial Polydrug Use on the Rewarding and Aversive Effects of the Novel Synthetic Cathinone Eutylone

open access: yesBrain Sciences, 2023
Background: As individual synthetic cathinones become scheduled and regulated by the Drug Enforcement Administration (DEA), new ones regularly are produced and distributed. One such compound is eutylone, a novel third-generation synthetic cathinone whose
Hayley N. Manke   +4 more
doaj   +1 more source

Differential Pulse Voltammetric Analysis of the New Psychoactive Drug 3β‐(4‐Fluorobenzoyloxy)tropane (fluorotropacocaine)

open access: yesElectroanalysis, Volume 38, Issue 5, May 2026.
First voltammetric characterization of fluorotropacocaine and development of a selective DPV method for real‐sample analysis. A Design of Experiments (DoE)‐optimized Florisil‐SPE cleanup enables up to 50× enrichment and sensitive detection in urine, with high selectivity against excipients, endogenous components, and co‐occurring new psychoactive ...
Giancarla Alberti   +4 more
wiley   +1 more source

Psychopathological Concomitants and Motivations Related to Misuse of Non‐Steroidal Anti‐Inflammatory Drugs and Paracetamol

open access: yesHuman Psychopharmacology: Clinical and Experimental, Volume 41, Issue 3, May 2026.
ABSTRACT Introduction Non‐steroidal anti‐inflammatory drugs (NSAIDs) and paracetamol are among the most commonly used medications worldwide. It has been suggested that the misuse of such medications is not uncommon. The objective of the present research was to explore prevalence, reported reasons and psychopathological concomitants related to NSAIDs ...
Francesco Saverio Bersani   +8 more
wiley   +1 more source

Fast Times in Federal Court and the Need for Flexibility [PDF]

open access: yes, 2018
The shifting landscape of criminal prosecutions involving designer drugs presents several novel legal issues. There are different ways to address these issues when they are the result of the production, possession, or distribution of as-of-yet ...
Moore, K. Michael
core   +1 more source

Analytical Challenges in Detecting New Psychoactive Substances in Anti‐Doping: A Proof‐of‐Concept Involving Pentedrone Metabolite

open access: yesDrug Testing and Analysis, Volume 18, Issue 4, Page 530-536, April 2026.
The paper describes an investigation related to the pentedrone norephedrine metabolite. The athlete's sample was analyzed using ultra‐performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS). According to the literature, this metabolite may originate from pentedrone, α‐pyrrolidinopentiophenone (PVP), or N‐ethylpentedrone (NEP).
D. Kwiatkowska   +8 more
wiley   +1 more source

Wherefore the Magic? The Evolutionary Role of Psilocybin in Nature

open access: yesEcology and Evolution, Volume 16, Issue 4, April 2026.
This study explores the evolutionary role of psilocybin, the psychedelic compound found in Psilocybe mushrooms. We provide the first experimental tests of defence and community‐level evidence for invertebrate responses to psilocybin‐producing fungi, revealing significant negative effects on invertebrate locomotion, development, and survival.
K. J. Matthews Nicholass   +16 more
wiley   +1 more source

Recreational use, analysis and toxicity of tryptamines [PDF]

open access: yes, 2015
The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs.
Mannocchi, Giulio   +3 more
core   +1 more source

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