Results 61 to 70 of about 13,766,532 (237)
“Cell-Free Synthetic Biology”: Synthetic Biology Meets Cell-Free Protein Synthesis [PDF]
Methods and Protocols, 2019 Since Nirenberg and Matthaei used cell-free protein synthesis (CFPS) to elucidate the genetic code in the early 1960s [...]
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Regression plane concept for analysing continuous cellular processes with machine learning
Nature Communications, 2021 High-content screening prompted the development of software enabling discrete phenotypic analysis of single cells. Here, the authors show that supervised continuous machine learning can drive novel discoveries in diverse imaging experiments and present ...
Abel Szkalisity +16 more
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Actinosomes: Condensate-Templated Containers for Engineering Synthetic Cells
ACS Synthetic Biology, 2022 Engineering synthetic cells has a broad appeal, from understanding living cells to designing novel biomaterials for therapeutics, biosensing, and hybrid interfaces.
K. Ganar, L. Leijten, S. Deshpande
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Molecular Communication Approaches for Wetware Artificial Life: A Workshop Report
ProceedingsOn 25 July 2023, a workshop entitled “Molecular Communication Approaches for Wetware Artificial Life” took place as a satellite event at the international conference ALIFE 2023 (The 2023 Conference on Artificial Life).
Pasquale Stano +7 more
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Dynamic microcompartmentation in synthetic cells [PDF]
Proceedings of the National Academy of Sciences, 2005 An experimental model for cytoplasmic organization is presented. We demonstrate dynamic control over protein distribution within synthetic cells comprising a lipid bilayer membrane surrounding an aqueous polymer solution. This polymer solution generally exists as two immiscible aqueous phases.
M Scott, Long +4 more
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A DNA segregation module for synthetic cells
bioRxiv, 2022 The bottom-up construction of an artificial cell requires the realization of synthetic cell division. Significant progress has been made towards reliable compartment division, yet mechanisms to segregate the DNA-encoded informational content are still in
Mai P. Tran +7 more
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Synthetic Biology Goes Cell-Free [PDF]
BMC Biology, 2019 Cell-free systems (CFS) have recently evolved into key platforms for synthetic biology applications. Many synthetic biology tools have traditionally relied on cell-based systems, and while their adoption has shown great progress, the constraints inherent to the use of cellular hosts have limited their reach and scope.
Tinafar, Aidan +2 more
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Light-activated assembly of connexon nanopores in synthetic cells
bioRxiv, 2022 During developmental processes and wound healing, activation of living cells occurs with spatiotemporal precision and leads to rapid release of soluble molecular signals, allowing communication and coordination between neighbors.
Ahmed Z. Sihorwala +3 more
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Data, 2018 Protein synthesis is at the core of bottom-up construction of artificial cellular mimics. Intriguingly, several reports have revealed that when a transcription–translation (TX–TL) kit is encapsulated inside lipid vesicles (or water-in-oil droplets), high
Paolo Carrara +4 more
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Droplet-Templated Synthetic Cells
, 2021 Summary Synthetic cells, also referred to as protocells, artificial cells, or minimal cells, are a type of engineered entities that mimic the features of biological cells and are promising for recapitulating cellular features and behaviors.
Luoran Shang, Yuanjin Zhao
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