Results 101 to 110 of about 3,003,336 (196)

Write and Read: Harnessing Synthetic DNA Modifications for Nanopore Sequencing. [PDF]

ACS Nano
Bertocchi U, Grunwald A, Goldner G, Eitan E, Avraham S, Dvir S, Deek J, Michaeli Y, Yao B, Listgarten J, Simpson JT, Timp W, Ebenstein Y.   +12 more
europepmc   +2 more sources

Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors

Nature Communications
The DNA damage response (DDR) protein DNA Polymerase θ (Polθ) is synthetic lethal with homologous recombination (HR) factors and is therefore a promising drug target in BRCA1/2 mutant cancers. We discover an allosteric Polθ inhibitor (Polθi) class with 4–
William Fried, Mrityunjay Tyagi, Leonid Minakhin, Gurushankar Chandramouly, Taylor Tredinnick, Mercy Ramanjulu, William Auerbacher, Marissa Calbert, Timur Rusanov, Trung Hoang, Nikita Borisonnik, Robert Betsch, John J. Krais, Yifan Wang, Umeshkumar M. Vekariya, John Gordon, George Morton, Tatiana Kent, Tomasz Skorski, Neil Johnson, Wayne Childers, Xiaojiang S. Chen, Richard T. Pomerantz   +22 more
doaj   +1 more source

Scalable Combinatorial Assembly of Synthetic DNA for Tracking Applications. [PDF]

Int J Mol Sci, 2023
Stuart JD, Wickenkamp NR, Davis KA, Meyer C, Kading RC, Snow CD.   +5 more
europepmc   +1 more source

Design, Mechanical Properties, and Dynamics of Synthetic DNA Filaments. [PDF]

Bioconjug Chem, 2023
Stenke LJ, Saccà B.
europepmc   +1 more source

synDNA-a Synthetic DNA Spike-in Method for Absolute Quantification of Shotgun Metagenomic Sequencing. [PDF]

mSystems, 2022
Zaramela LS, Tjuanta M, Moyne O, Neal M, Zengler K.   +4 more
europepmc   +1 more source

Amphiphiles Formed from Synthetic DNA-Nanomotifs Mimic the Stepwise Dispersal of Transcriptional Clusters in the Cell Nucleus. [PDF]

Nano Lett, 2023
Tschurikow X, Gadzekpo A, Tran MP, Chatterjee R, Sobucki M, Zaburdaev V, Göpfrich K, Hilbert L.   +7 more
europepmc   +1 more source

Síntese, caracterização e estudo de interação com o dna de novos complexos de cobre(ii) com o ligante“dppz” [PDF]

, 2008
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Curso de Química.A partir da compreensão mais detalhada de como os sítios do DNA são atingidos com especificidade poderá levar a obtenção de novos ...
Policarpi, Everton de Britto
core  

Embeddability of centrosymmetric matrices capturing the double-helix structure in natural and synthetic DNA. [PDF]

J Math Biol, 2023
Ardiyansyah M, Kosta D, Roca-Lacostena J.   +2 more
europepmc   +1 more source

A synthetic DNA template for fast manufacturing of versatile single epitope mRNA. [PDF]

Mol Ther Nucleic Acids, 2022
de Mey W, De Schrijver P, Autaers D, Pfitzer L, Fant B, Locy H, Esprit A, Lybaert L, Bogaert C, Verdonck M, Thielemans K, Breckpot K, Franceschini L.   +12 more
europepmc   +1 more source

Collective cell behaviors manipulated by synthetic DNA nanostructures. [PDF]

Fundam Res, 2023
Wang X, Xing X, Lu S, Du G, Zhang Y, Ren Y, Sun Y, Sun J, Fan Q, Liu K, Wang F, Ye F.   +11 more
europepmc   +1 more source