A multi-country comparative study of two treponemal tests for the serodiagnosis of syphilis amongst men who have sex with men (MSM): Chemo-luminescent assay vs Treponema pallidum particle agglutination assay [PDF]
BMC Infectious DiseasesIntroduction International guidelines recommend routine screening for syphilis (aetiological agent: Treponema pallidum subspecies pallidum) amongst key populations and vulnerable populations using tests detecting treponemal and non-treponemal antibodies.
Lorenzo Gios +13 more
doaj +8 more sources
Evaluation of the Diagnostic Algorithms for Serodiagnosis of Syphilis
Japanese Journal of Infectious Diseases, 2022 We analyzed the performance parameters of the traditional and reverse algorithms to determine which is more convenient for serodiagnosis of syphilis. In total, 4,789 serum samples were obtained from a cross-sectional study. Venereal Disease Research Laboratory (VDRL), Treponema pallidum hemagglutination assay (TPHA), and chemiluminescent microparticle ...
Rukiye Berkem +2 more
semanticscholar +7 more sources
Liposomes: from August Wassermann to Vaccines Against COVID-19 [PDF]
ADMET and DMPK, 2023 Background and Purpose: The development of vaccines against the SARS-CoV-2 virus has become a big challenge for many countries in 2020-2022. mRNA vaccines were shown to be effective and safe and have been widely used worldwide in the fight against the ...
Ganna Grygorieva +2 more
doaj +6 more sources
The tradition algorithm approach underestimates the prevalence of serodiagnosis of syphilis in HIV-infected individuals. [PDF]
PLoS Neglected Tropical Diseases, 2017 Currently, there are three algorithms for screening of syphilis: traditional algorithm, reverse algorithm and European Centre for Disease Prevention and Control (ECDC) algorithm. To date, there is not a generally recognized diagnostic algorithm.
Bin Chen +5 more
doaj +4 more sources
Evaluation of the boson chemiluminescence immunoassay as a first-line screening test in the ECDC algorithm for syphilis serodiagnosis in a population with a high prevalence of syphilis. [PDF]
J Clin Microbiol, 2015 Qiu XH +16 more
europepmc +3 more sources
International Journal of Infectious Diseases, 2019 Objectives: With the development of the automated treponemal test, new syphilis serodiagnosis algorithms, reverse algorithm, and European Centre for Disease Prevention and Control (ECDC) algorithm have been recommended recently.
Seungjun Lee +5 more
doaj +2 more sources
Serodiagnosis of Syphilis [PDF]
Medical Clinics of North America, 1972 n ...
R.W. Fairbrother, A.L.P. Peeney
+9 more sources
Kazan medical journal, 2021 Stiden (Bp. Delo, 1924, No. 10) of all sedimentary reactions proposed for the diagnosis of syphilis, especially recommends the Kahn reaction, which, on the one hand, is distinguished by the simplicity of technical implementation, and on the other hand ...
V. G.
semanticscholar +3 more sources
Assessment of recombinant antigens Tp0100 and Tp1016 of Treponema pallidum for serological diagnosis of syphilis. [PDF]
J Clin Lab Anal, 2022 SDS‐PAGE analysis of the expression and purification of recombinant proteins. (A, B) Tp0100 (22 kDa); (C, D) Tp1016 (39 kDa). M: molecular mass markers; N:noninduced; I: induced with IPTG; P: purification. Western blotting identification of recombinant proteins Tp0100 and Tp1016 with sera from normal rabbits (1), sera from uninfected human (2), anti ...
Chen D +11 more
europepmc +2 more sources
Sensitivity and specificity of a syphilis rapid diagnostic test in blood donors’ samples [PDF]
Brazilian Journal of Infectious Diseases, 2023 Rapid Diagnostic Tests (RDT) are useful to identify syphilis cases, particularly for hard-to-reach populations and if laboratory services are scarce. However, RDT performance may be suboptimal.
Carolina Arai +6 more
doaj +2 more sources