The tradition algorithm approach underestimates the prevalence of serodiagnosis of syphilis in HIV-infected individuals [PDF]
Currently, there are three algorithms for screening of syphilis: traditional algorithm, reverse algorithm and European Centre for Disease Prevention and Control (ECDC) algorithm. To date, there is not a generally recognized diagnostic algorithm.
Xiaorong Peng +2 more
exaly +3 more sources
A multi-country comparative study of two treponemal tests for the serodiagnosis of syphilis amongst men who have sex with men (MSM): Chemo-luminescent assay vs Treponema pallidum particle agglutination assay [PDF]
Introduction International guidelines recommend routine screening for syphilis (aetiological agent: Treponema pallidum subspecies pallidum) amongst key populations and vulnerable populations using tests detecting treponemal and non-treponemal antibodies.
Lorenzo Gios +13 more
doaj +5 more sources
Performance of Treponema pallidum recombinant proteins in the serological diagnosis of syphilis.
Syphilis serodiagnosis is challenging because distinct clinical forms of the infection may influence serological performance and discordant results between tests make clinical decisions difficult.
Ângelo Antônio Oliveira Silva +10 more
doaj +2 more sources
Investigating latent syphilis in HIV treatment-experienced Ethiopians and response to therapy.
ObjectivesWe investigated people with HIV (PWH) receiving combination antiretroviral therapy (cART) for latent syphilis infection prevalence, risk factors, treatment response, and neurosyphilis.MethodsA prospective follow-up study was conducted on PWH ...
Selamawit Girma, Wondwossen Amogne
doaj +2 more sources
The data presented in this article are related to the research article entitled “Performance of novel infection phase-dependent antigens in syphilis serodiagnosis and treatment efficacy determination”.
Wen Liu +5 more
doaj +2 more sources
Objectives: With the development of the automated treponemal test, new syphilis serodiagnosis algorithms, reverse algorithm, and European Centre for Disease Prevention and Control (ECDC) algorithm have been recommended recently.
Seung Jun Lee, Hui-Jin Yu, Sangeun Lim
exaly +3 more sources
Evaluating Frequency, Diagnostic Quality, and Cost of Lyme Borreliosis Testing in Germany: A Retrospective Model Analysis [PDF]
Background. Data on the economic impact of Lyme borreliosis (LB) on European health care systems is scarce. This project focused on the epidemiology and costs for laboratory testing in LB patients in Germany. Materials and Methods. We performed a sentinel analysis of epidemiological and medicoeconomic data for 2007 and 2008.
I. Müller +13 more
wiley +2 more sources
Comparative analysis of the Traditional, Reverse and European Centre for Disease Prevention and Control algorithms and utilization of WHO NET software for syphilis serodiagnosis in a tertiary care hospital in Chengalpet, South India [PDF]
Background: Syphilis is a Sexually Transmitted Disease (STD) caused by Treponema pallidum with significant public health importance. Based on the clinical presentation syphilis is classified into primary, secondary, tertiary and latent syphilis.
Abirami Lakshmy Jayachandran +3 more
doaj +2 more sources
Recombinant antigen-based immuno-slot blot method for serodiagnosis of syphilis [PDF]
Three recombinant antigens of Treponema pallidum Nichols strain were fused with GST, cloned and expressed in Escherichia coli, resulting in high levels of GST-rTp47 and GST-rTp17 expression, and supplementation with arginine tRNA for the AGR codon was ...
N.S. Sato +5 more
doaj +2 more sources

