Results 21 to 30 of about 2,033 (186)

Evaluating the diagnostic accuracy of TpN17 and TmpA recombinant proteins in syphilis detection: a phase II study [PDF]

Frontiers in Microbiology
Syphilis is a sexually transmitted infection (STI) caused by the spiral bacterium Treponema pallidum. Diagnosis is based on epidemiology, clinical and serology, but serodiagnosis is challenging because distinct clinical forms of the infection may ...
Ângelo Antônio Oliveira Silva, Ângelo Antônio Oliveira Silva, Ayla Araújo Lima, Larissa Carvalho Medrado Vasconcelos, Rosângela Andrade Almeida, Natália Erdens Maron Freitas, Talita Andrade Oliva, Miralba Freire de Carvalho Ribeiro da Silva, Fabricio Klerynton Marchini, Fabricio Klerynton Marchini, Nilson Ivo Tonin Zanchin, Nilson Ivo Tonin Zanchin, Isadora Cristina de Siqueira, Isadora Cristina de Siqueira, Fred Luciano Neves Santos, Fred Luciano Neves Santos   +15 more
doaj   +2 more sources

Acquired syphilis: update on clinical, diagnostic and therapeutic aspects [PDF]

Anais Brasileiros de Dermatologia
Syphilis, an infection caused by Treponema pallidum, transmitted predominantly through sexual contact, affects several organs, causing skin, mucous membranes and systemic lesions.
Carolina Talhari, Kaique Arriel, Marcio Soares Serra, John Verrinder Veasey   +3 more
doaj   +2 more sources

Comparison of Semi-Quantitative RPR Test and TPHA for Serodiagnosis of Syphilis

National Journal of Community Medicine, 2017
Introduction: A reactive RPR should always be confirmed with treponemal test like TPHA in suspected syphilis patients to rule out biological false positive cases.
Nasiruddin M Shaikh, Tanmay K Mehta, Parul D Shah   +2 more
doaj   +1 more source

Prospects for the application of recombinant antigens Treponema pallidum TР0163 and TР0971 in enzyme-linked immunosorbent assay for the detection of immunoglobulin M in the serum of syphilis patients: A pilot observational study

Кубанский научный медицинский вестник
Background. The enzyme-linked immunosorbent assay based on recombinant analogues of Treponema pallidum immunogenic proteins enables the diagnosis of syphilis by determining immunoglobulin G and immunoglobulin M. The detection of specific immunoglobulin M
N. V. Arbuzova, M. V. Shpilevaya, G. L. Katunin, N. Yu. Nosov   +3 more
doaj   +2 more sources

Syphilis in pregnancy: A practical guide for prenatal care providers. [PDF]

Int J Gynaecol Obstet
Abstract Syphilis during pregnancy remains a persistent global public health challenge. Untreated or inadequately treated syphilis infection during pregnancy contributes significantly to preventable perinatal morbidity and mortality. In the last five years, a resurgence of syphilis among pregnant women in several regions has led to a concerning rise in
Desjardins AA, Amaral E, Miranda J, Pasupathy D, Martins ML, Buga E, Aronoff D, Money D, Boucoiran I, FIGO Committee on Infections During Pregnancy and FIGO Committee on Health Systems Strengthening.   +9 more
europepmc   +2 more sources

The difficulties of diagnosis of neurosyphilis at the modern stage

Лечащий Врач, 2021
At the modern stage in Russia, we can observe the tendency of increase in recording cases of neurosyphilis against the background of reduction of morbidity rate of syphilitic infection in general.
T. L. Vizilo, T. V. Poponnikova, I. F. Fedoseeva, E. D. Vasenina   +3 more
doaj   +1 more source

Assessment of recombinant antigens Tp0100 and Tp1016 of Treponema pallidum for serological diagnosis of syphilis

Journal of Clinical Laboratory Analysis, Volume 36, Issue 9, September 2022., 2022
SDS‐PAGE analysis of the expression and purification of recombinant proteins. (A, B) Tp0100 (22 kDa); (C, D) Tp1016 (39 kDa). M: molecular mass markers; N:noninduced; I: induced with IPTG; P: purification. Western blotting identification of recombinant proteins Tp0100 and Tp1016 with sera from normal rabbits (1), sera from uninfected human (2), anti ...
Dejun Chen, Siqian Wang, Yuxing He, Yue Fu, Feijun Zhao, Xiuping Zhou, Haoquan Yin, Jia Wan, Yunting Huang, Yimou Wu, Longgu Cao, Tiebing Zeng   +11 more
wiley   +1 more source

Improved Performance of ELISA and Immunochromatographic Tests Using a New Chimeric A2‐Based Protein for Human Visceral Leishmaniasis Diagnosis

Journal of Immunology Research, Volume 2021, Issue 1, 2021., 2021
Summary. Human visceral leishmaniasis (VL) is a major public health problem worldwide, leading to significant mortality rates if not properly treated and controlled. Precise identification of infected patients is essential to establish treatment and control measures.
Maria Marta Figueiredo, Anna R. R. dos Santos, Lara C. Godoi, Natália S. de Castro, Bruno C. de Andrade, Sarah A. R. Sergio, Selma M. B. Jerônimo, Edward J. de Oliveira, Ruth T. Valencia-Portillo, Lucilândia M. Bezerra, Hiro Goto, Maria C. A. Sanchez, Caroline Junqueira, Santuza M. R. Teixeira, Flávio G. da Fonseca, Ricardo T. Gazzinelli, Ana Paula Fernandes, Gabriela Santos-Gomes   +17 more
wiley   +1 more source

The Clinical Characteristics and Serological Outcomes of Infants With Confirmed or Suspected Congenital Syphilis in Shanghai, China: A Hospital-Based Study

Frontiers in Pediatrics, 2022
BackgroundCongenital syphilis (CS) is the infection of an infant or fetus with Treponema pallidum. The aim of this study was to investigate the clinical features and outcomes of serology reversion in infants diagnosed with confirmed or suspected ...
Yi Dai, Guanpeng Zhai, Shulian Zhang, Chao Chen, Zhihua Li, Wenjing Shi, Wenjing Shi   +6 more
doaj   +1 more source

A case of secondary syphilis misdiagnosed as psoriasis vulgaris: Discover the real cause beyond the surface with reflection confocal microscopy and leave the great imitator nowhere to hide

, 2023
Skin Research and Technology, Volume 29, Issue 6, June 2023.
Jianfeng Zhang, Xia Li, Dongmei Shi
wiley   +1 more source