Results 41 to 50 of about 666,830 (274)

HIV and AIDS in the Russian Federation : prisons as a case study of risk environments and agency [PDF]

, 2017
This thesis explores Russian prisons as risk environments for the spread of HIV through intravenous drug use. The Russian HIV epidemic is extremely fast growing, and though exact prevalence rates are unknown, the epidemic is now considered generalized as
Severson, Jamie LeeAnn
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Impact of an air bubble within the syringe on test results obtained with a modern blood gas analyzer [PDF]

Journal of Medical Biochemistry
Background: Minimizing air aspiration by carefully filling blood gas syringes is crucial to prevent air contamination from causing undesirable variations in gasses and other molecules.
Pighi Laura, Salvagno Gian Luca, Ferraro Roberta, Celegon Giovanni, Henry Brandon M., Lippi Giuseppe   +5 more
doaj   +1 more source

Гидравлический расчёт проточного тракта медицинского шприца [PDF]

, 2008
Проведено аналіз типових недоліків медичних шприців, що випускаються серійно. Розроблено алгоритм розрахунку проточного тракту шприца, що дозволяє оцінити конструктивні та ергономічні параметри шприца на стадії проектування.
Морокко, И. И., Седач, Виктор Валентинович   +1 more
core  

Freeform Fabrication of Biological Scaffolds by Projection Photopolymerization [PDF]

, 2007
This article presents a micro-manufacturing method for direct, projection printing of 3- dimensional (3D) scaffolds for applications in the field of tissue engineering by using a digital micro-mirror-array device (DMD) in a layer-by-layer process ...
Chen, Shaochen, Han, Li-Hsin, Mapili, Gazill, Roy, Krishnendu   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The effect of mepolizumab dosage form on treatment outcomes in severe asthma

Frontiers in Medicine
BackgroundA monoclonal antibody such as mepolizumab typically first appears as a parenteral lyophilized formulation (LYO), then as various parenteral solution forms, and finally as a self-administered form at homecare.
Martina Vetchá, Kateřina Kubová, Constantinos Glynos, Sylvie Pavloková, Irena Krčmová, Irena Krčmová, Eva Voláková, Eva Voláková, Ondřej Fibigr, Ondřej Fibigr, Beáta Hutyrová, Beáta Hutyrová, Alena Vlachová, Jiří Zeman, David Vetchý   +14 more
doaj   +1 more source

Evaluation of Endotracheal Tube Cuff Pressure and the Use of Three Cuff Inflation Syringe Devices in Dogs

Frontiers in Veterinary Science, 2020
Over-inflation of an endotracheal tube (ETT) cuff may lead to tracheal mucosal irritation, tracheal wall ischemia or necrosis, whereas under-inflation increases the risk of pulmonary aspiration as well as leaking anesthetic gas and polluting the ...
Wan-Chu Hung, Jeff C. Ko, Ann B. Weil, Hsin-Yi Weng   +3 more
doaj   +1 more source

Micro-fluid exchange coupling apparatus [PDF]

, 1980
In a macro-fluid exchange, a hollow needle, such as a syringe needle, is provided for penetrating the fluid conduit of the animal. The syringe needle is coupled to a plenum chamber having an inlet and outlet port.
Johnson, J. E., Jr., Swartz, P. F.
core   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source