Results 21 to 30 of about 75,257 (264)

Needle stick injuries among dental students: risk factors and recommendations for prevention [PDF]

open access: yesLibyan Journal of Medicine, 2012
Aim: To evaluate the risk factors of needle stick injuries (NSIs) sustained by undergraduate dental students and nurse students at the King's College London (KCL) Dental Institute.
Kamis Gaballah   +3 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Examining unsafe injection practices associated with auto-disable (AD) syringes: a systematic review

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Auto-disable (AD) syringes are specifically designed to prevent syringe reuse. However, the notion that specific AD syringe designs may be unsafe due to reuse concerns related to the syringe’s activation point has surfaced.
Anokhi Ali Khan   +7 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

A national physician survey on prescribing syringes as an HIV prevention measure

open access: yesSubstance Abuse Treatment, Prevention, and Policy, 2009
Background Access to sterile syringes is a proven means of reducing the transmission of human immunodeficiency virus (HIV), viral hepatitis, and bacterial infections among injection drug users. In many U.S.
Macalino GE   +6 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Optimal provision of opiate substitution therapy and needle and syringe programmes: a multi-method realist evaluation

open access: yesHealth Technology Assessment
Background The barriers and facilitators to engagement with Opiate Substitute Treatment and Needle and Syringe Provision need to be better understood to develop interventions to attract people into services.
Peter McCulloch   +11 more
doaj   +1 more source

In vitro assessment of needle and irrigant penetration when using different irrigation needle tips

open access: yesBiomaterial Investigations in Dentistry
Objective: The aim of this study was to compare the needle and irrigant penetration depth of a newly developed multi-vented polymer needle (30G), with three established needle designs – an open-ended metal needle (30G), a side-vented polymer needle (30G)
Saleha Hussain   +2 more
doaj   +1 more source

Safer Enteral Nutrition Syringes

open access: yesPatient Safety, 2020
Hundreds of thousands of patients receive enteral nutrition (EN) or tube feeding each year in U.S. hospitals, and many more in long-term care and home settings.
Peggi Guenter, Beth Lyman
doaj   +1 more source

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