Results 31 to 40 of about 80,654 (260)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

In vitro assessment of needle and irrigant penetration when using different irrigation needle tips

Biomaterial Investigations in Dentistry
Objective: The aim of this study was to compare the needle and irrigant penetration depth of a newly developed multi-vented polymer needle (30G), with three established needle designs – an open-ended metal needle (30G), a side-vented polymer needle (30G)
Saleha Hussain, Lars Bjørndal, Merete Markvart   +2 more
doaj   +1 more source

A protocol for microbiologically safe preparation, storage, and use of autologous serum eye-drops in low-income countries

Journal of Infection in Developing Countries, 2015
Introduction: The study aimed to investigate whether the preparation, storage, and use of autologous serum in insulin syringes is microbiologically safe. Methodology: Blood samples (10 mL) were obtained from 10 volunteers.
Francesco Blasetti, Donatella Usai, Salvatore Sotgia, Ciriaco Carru, Stefania Zanetti, Antonio Pinna   +5 more
doaj   +1 more source

Safer Enteral Nutrition Syringes

Patient Safety, 2020
Hundreds of thousands of patients receive enteral nutrition (EN) or tube feeding each year in U.S. hospitals, and many more in long-term care and home settings.
Peggi Guenter, Beth Lyman
doaj   +1 more source

Accuracy and Reproducibility of Injections from Prefilled “Code Cart” Syringes Compared to Standard Polypropylene Syringes

, 2023
Class of 2023 Abstract and PosterSpecific Aims: To evaluate the accuracy and reproducibility of small-volume injections from prefilled syringes and different sizes of polypropylene syringes.
Kim, Yoona
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Optimal provision of opiate substitution therapy and needle and syringe programmes: a multi-method realist evaluation

Health Technology Assessment
Background The barriers and facilitators to engagement with Opiate Substitute Treatment and Needle and Syringe Provision need to be better understood to develop interventions to attract people into services.
Peter McCulloch, April Shaw, Gail Gilchrist, Catriona Matheson, Margaret Maxwell, Joanne Neale, Gareth Myring, Hugh McLeod, Matt Hickman, Peter Vickerman, Alison Munro, Steve MacGillivray   +11 more
doaj   +1 more source

HCV serostatus and injection sharing practices among those who obtain syringes from pharmacies and directly and indirectly from syringe services programs in rural New England

Addiction Science & Clinical Practice, 2023
Background Among people who inject drugs (PWID), obtaining syringes via syringe services programs (SSPs) and pharmacies reduces injection sharing practices associated with hepatitis C virus (HCV).
Eric Romo, Abby E. Rudolph, Thomas J. Stopka, Bo Wang, Bill M. Jesdale, Peter D. Friedmann   +5 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Contact with hospital syringes containing body fluids: implications for medical waste management regulation

Salud Pública de México, 2003
OBJECTIVE: To determine amount of syringes used in the hospital and extent of contact with blood and body fluids of these syringes. MATERIAL AND METHODS: Syringe use was surveyed at a tertiary care center for one week; syringes were classified into the ...
Volkow Patricia, Jacquemin Bénédicte, Vilar-Compte Diana, Castillo José Ramón   +3 more
doaj