Results 51 to 60 of about 154,072 (293)

Release of silicone oil droplets from syringes

open access: yesInternational Journal of Retina and Vitreous, 2019
Background Intravitreal silicone oil droplets have been found in the vitreous. The aim of this study is to compare the rates of silicone oil released by different brands of commonly used syringes for intravitreal injection after agitation by flicking ...
Gustavo Barreto Melo   +8 more
doaj   +1 more source

The Public Health Impact of Needle Exchange Programs in the United States and Abroad: Summary, Conclusions, and Recommendations [PDF]

open access: yes, 1993
The goal of the project was: "To assess the public health impact of needle exchange programs." Fourteen research questions were identified; Chapters 5 through 18 of Volume I of the report each address one of these research questions.
Arthur L. Reingold, Peter Lurie
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

A global health partnership's use of time-limited support to catalyze health practice change: the case of GAVI's Injection Safety Support. [PDF]

open access: yesPLoS ONE, 2010
This paper presents the findings of a study to assess the effectiveness and sustainability of a GAVI (Global Alliance of Vaccines and Immunization) sponsored, time-limited Injection Safety (INS) support.
Ann Levin   +5 more
doaj   +1 more source

Reducing Infectious Diseases in the U.S.: Focus on HIV/AIDS and Hepatitis [PDF]

open access: yes, 2009
Offers arguments for the efficacy of needle exchange programs in reducing infections among drug users and against the ban on using federal funds for such programs.

core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Injecting equipment schemes for injecting drug users : qualitative evidence review [PDF]

open access: yes, 2009
This review of the qualitative literature about needle and syringe programmes (NSPs) for injecting drug users (IDUs) complements the review of effectiveness and cost-effectiveness.
Akhionbare, Kate   +3 more
core  

Big Syringe, Little Syringe [PDF]

open access: yesJournal of Cardiothoracic and Vascular Anesthesia, 2020
Kelly A, Machovec, Warwick A, Ames
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

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