Results 121 to 130 of about 29,946,329 (341)

Individual heterogeneity generates explosive system network dynamics

open access: yes, 2017
Individual heterogeneity is a key characteristic of many real-world systems, from organisms to humans. However its role in determining the system's collective dynamics is typically not well understood.
Johnson, Neil F., Manrique, Pedro D.
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Launch dynamics modeling and simulation of box-type multiple launch rocket system considering plane clearance contact

open access: yesDefence Technology
As the performance of the box-type multiple launch rocket system (BMLRS) improves, its mechanical structures, particularly the plane clearance design between the slider on the rocket and the guide inside the launch canister, have grown increasingly ...
Jinxin Tang   +5 more
doaj   +1 more source

Investigations into wastewater composition focusing on nonwoven wet wipes

open access: yesTechnical Transactions, 2017
This paper summarizes the problems caused for wastewater systems by changing wastewater composition, especially the increasing use of nonwoven wet wipes and their disposal via the toilet.
Mitchell Raja-Louisa   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Contact mechanics and friction: Role of adhesion

open access: yesFriction
This paper presents an overview of the role of adhesion in various tribological phenomena. We discuss (1) adhesion and adhesive hysteresis in rough contacts, (2) adhesive contribution to dry friction, (3) properties of adhesive contacts under tangential ...
Valentin L. Popov   +2 more
doaj   +1 more source

Multi-Body Ski Jumper Model with Nonlinear Dynamic Inversion Muscle Control for Trajectory Optimization

open access: yesProceedings, 2018
This paper presents an approach to model a ski jumper as a multi-body system for an optimal control application. The modeling is based on the constrained Newton-Euler-Equations.
Patrick Piprek   +6 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Blind-Matched Filtering for Speech Enhancement with Distributed Microphones

open access: yesJournal of Electrical and Computer Engineering, 2012
A multichannel noise reduction and equalization approach for distributed microphones is presented. The speech enhancement is based on a blind-matched filtering algorithm that combines the microphone signals such that the output SNR is maximized.
Sebastian Stenzel, Jürgen Freudenberger
doaj   +1 more source

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