Results 71 to 80 of about 143,113 (265)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
A k-Dimensional System of Fractional Neutral Functional Differential Equations with Bounded Delay
Abstract and Applied Analysis, 2014 In 2010, Agarwal et al. studied the existence of a one-dimensional fractional neutral functional differential equation. In this paper, we study an initial value problem for a class of k-dimensional systems of fractional neutral functional differential ...
Dumitru Baleanu +2 more
doaj +1 more source
Abstract functional-differential equations and reaction-diffusion systems [PDF]
, 1990 R. H. Martin, Hal L. Smith
openalex +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Functional Integral Approach to the Solution of a System of Stochastic Differential Equations
EPJ Web of Conferences, 2018 A new method for the evaluation of the characteristics of the solution of a system of stochastic differential equations is presented. This method is based on the representation of a probability density function p through a functional integral.
Ayryan Edik +4 more
doaj +1 more source
Erratum: Density functional theory for open-shell systems using a local-scaling transformation scheme. II. Euler-Lagrange equation for f(r) versus that for ?(r) [PDF]
, 1998 R. L. Pavlov +3 more
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Conservation Laws of Discrete Korteweg-de Vries Equation
Symmetry, Integrability and Geometry: Methods and Applications, 2005 All three-point and five-point conservation laws for the discrete Korteweg-de Vries equations are found. These conservation laws satisfy a functional equation, which we solve by reducing it to a system of partial differential equations.
Olexandr G. Rasin, Peter E. Hydon
doaj