Results 141 to 150 of about 42,961 (301)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Principles in Patterns (PiP) : User Acceptance Testing of Course and Class Approval Online Pilot (C-CAP) [PDF]

, 2012
The PiP Evaluation Plan documents four distinct evaluative strands, the first of which entails an evaluation of the PiP system pilot (WP7:37 – Systems & tool evaluation).
Macgregor, George
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

DESAIN UI/UX SISTEM PENGELOLAAN DATA BENCANA BPBD KOTA BATU DENGAN METODE DESIGN THINKING [PDF]

The Regional Disaster Management Agency (BPBD) is a government agency that has the task of handling disasters both from pre-disaster (preparedness factor), during disasters (disaster emergency conditions), post-disaster (recovery phase).
Samudra, Ronaldo Rizki
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

EVALUASI DAN PERBAIKAN DESAIN ANTARMUKA PADA WEBSITE PELAYANAN DINAS KEPENDUDUKAN DAN PENCATATAN SIPIL KABUPATEN KOTAWARINGIN TIMUR MENGGUNAKAN METODE LEAN UX [PDF]

The Civil Registry and Population Office of Kotawaringin Timur Regency developed a system in the form of a website for online services to the community.
Darmawan, Ilham
core  

EVALUASI USABILITY GOOGLE CLASSROOM PADA MAHASISWA MENGGUNAKAN SYSTEM USABILITY SCALE (SUS)

JATI (Jurnal Mahasiswa Teknik Informatika)
Di era digital, perkembangan teknologi telah mengubah sistem pembelajaran, salah satunya dengan hadirnya platform E-learning seperti Google Classroom. Platform ini banyak digunakan di berbagai institusi pendidikan untuk mendukung proses pembelajaran daring.
Ifun Romadoni Alfarosi, Prita Dellia, Fajar Agung Cahyo Pratama, Aldi Alpinus Tarigan, Moh Nurdin Syarif   +4 more
openaire   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

A tale of two studies [PDF]

, 2013
Running user evaluation studies is a useful way of getting feedback on partially or fully implemented software systems. Unlike hypothesis-based testing (where specific design decisions can be tested or comparisons made between design choices) the aim is ...
Bowen, Judy, Reeves, Steve, Schweer, Andrea   +2 more
core  

Analisa Usability Portal Bacaleg PKN Menggunakan Metode System Usability Scale (SUS)

SATIN - Sains dan Teknologi Informasi
The Portal Bacaleg PKN is a website-based application created by PT. Internusa Cipta Solusi Perdana is used by one of the political parties participating in the 2024 election to process voting data during the election period. In order to support the update and implementation of the next nomination stage, the author proposes to measure the level of ...
Arumny Zahroh, Laela Kurniawati
openaire   +1 more source