This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Genetic Polymorphisms of Vascular Endothelial Growth Factor in Neonatal Pathologies: A Systematic Search and Narrative Synthesis of the Literature [PDF]
Monica Hășmășanu +4 more
openalex +1 more source
Amblyopia and quality of life: a systematic review [PDF]
Background/Aims Amblyopia is a common condition which can affect up to 5% of the general population. The health-related quality of life (HRQoL) implications of amblyopia and/or its treatment have been explored in the literature.
A Göransson +53 more
core +6 more sources
Systematic studies of the literature can be done in different ways. In particular, different guidelines propose different first steps in their recommendations, e.g. start with search strings in different databases or start with the reference lists of a starting set of papers.
Jalali, Samireh, Wohlin, Claes
openaire +3 more sources
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Economic evidence for the prevention and treatment of atopic eczema: a protocol for a systematic review [PDF]
Background: Eczema, synonymous with atopic eczema or atopic dermatitis, is a chronic skin disease that has a similar impact on health-related quality of life as other chronic diseases.
AS Paller +18 more
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Information sources for obesity prevention policy research: a review of systematic reviews
Background Systematic identification of evidence in health policy can be time-consuming and challenging. This study examines three questions pertaining to systematic reviews on obesity prevention policy, in order to identify the most efficient search ...
Rosie Hanneke, Sabrina K. Young
doaj +1 more source
Background Systematic reviews (SRs) are considered one of the most reliable types of studies in evidence-based medicine. SRs rely on a comprehensive and systematic data gathering, including the search of academic literature databases. This study aimed to
Tobias Justesen +2 more
doaj +1 more source
A Systematic Review Evaluating Psychometric Properties of Parent or Caregiver Report Instruments on Child Maltreatment: Part 1: Content Validity [PDF]
Aims: Child maltreatment (CM) is a serious public health issue, affecting over half of all children globally. Although most CM is perpetrated by parents or caregivers and their reports of CM is more accurate than professionals or children, parent or ...
Aunio, Pirjo +4 more
core +3 more sources

