Results 91 to 100 of about 1,888,501 (343)

Amblyopia and quality of life: a systematic review [PDF]

, 2010
Background/Aims Amblyopia is a common condition which can affect up to 5% of the general population. The health-related quality of life (HRQoL) implications of amblyopia and/or its treatment have been explored in the literature.
A Göransson, A Searle, A Searle, AL Webber, AL Webber, B Chua, C Leach, C Schmucker, C Schmucker, C Williams, D Newsham, D Newsham, D Satterfield, DE Stull, E Kaltenthaler, E Stifter, EA Packwood, EE Birch, EP Steinberg, ES van de Graaf, ES van de Graaf, ES van de Graaf, HW Marsh, J Brazier, J Carlton, J Carlton, J Felius, J Felius, J Horwood, JM Holmes, JM Holmes, JS Rahi, JW Varni, JW Varni, K Koklanis, K Sabri, L Dias, L Dias, LC Parkes, M Dixon-Woods, M Schumacher, M Vianya-Estopa, MJ Christie, MK Margolis, MS Lewis-Jones, Pediatric Eye Disease Investigator Group, RP Rutstein, S Hrisos, S Jackson, SA Clarke, SE Loudon, SE Loudon, SR Cole, YF Choong   +53 more
core   +6 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Exploring search strategy for systematic literature review: evidence from the International Journal of Management Reviews

Business: Theory and Practice
Systematic literature reviews (SLRs) advance management theory and practice by synthesizing knowledge in a structured and transparent manner. However, inconsistent reporting of search strategies limits replicability and methodological rigor.
Marek Szarucki, Andriejus Sadauskis, Alma Mačiulytė-Šniukienė, Oskar Kosch   +3 more
doaj   +1 more source

Literature searching for social science systematic reviews: consideration of a range of search techniques [PDF]

Health Information & Libraries Journal, 2010
AbstractBackground:  Literature for a systematic review on the student experience of e‐learning is located across a range of subject areas including health, education, social science, library and information science.Objectives:  To assess the merits and shortcomings of using different search techniques in retrieval of evidence in the social science ...
Diana, Papaioannou, Anthea, Sutton, Christopher, Carroll, Andrew, Booth, Ruth, Wong   +4 more
openaire   +2 more sources

Economic evidence for the prevention and treatment of atopic eczema: a protocol for a systematic review [PDF]

, 2016
Background: Eczema, synonymous with atopic eczema or atopic dermatitis, is a chronic skin disease that has a similar impact on health-related quality of life as other chronic diseases.
AS Paller, Centre for reviews and dissemination (CRD), D Husereau, H Nankervis, H Williams, HC Williams, J Buchanan, J Glanville, J Kay, JK Schofield, JM Batchelor, KLE Hon, L Shamseer, M Futamura, RM Emerson, RM Herd, S Lewis‐jones, Z Philips, Z Philips   +18 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Dynamic stabilization versus fusion for treatment of degenerative spine conditions. [PDF]

, 2011
Study design Comparative effectiveness review.Study rationale Spinal fusion is believed to accelerate the degeneration of the vertebral segment above or below the fusion site, a condition called adjacent segment disease (ASD).
Chou, Dean, Ecker, Erika, Lau, Darryl, Skelly, Andrea   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Visual and Textual Programming Languages: A Systematic Review of the Literature [PDF]

, 2017
It is well documented, and has been the topic of much research, that Computer Science courses tend to have higher than average drop out rates at third level. This is a problem that needs to be addressed with urgency but also caution.
Mooney, Aidan, Noone, Mark
core   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source