Results 71 to 80 of about 1,921,675 (302)

Review of the evidence for adolescent and young person specific, community-based health services for NHS managers [PDF]

, 2015
Purpose – The purpose of this paper is to provide an overview of the evidence surrounding the design and delivery of adolescent-specific health services for young people aged 14-25.
Ryan, Gemma
core   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Defining the process to literature searching in systematic reviews: a literature review of guidance and supporting studies

BMC Medical Research Methodology, 2018
Background Systematic literature searching is recognised as a critical component of the systematic review process. It involves a systematic search for studies and aims for a transparent report of study identification, leaving readers clear about what was
Chris Cooper, Andrew Booth, Jo Varley-Campbell, Nicky Britten, Ruth Garside   +4 more
doaj   +1 more source

Mitteilungen aus der Arbeitsgemeinschaft Evidenzbasierte Medizin der AGMB

GMS Medizin – Bibliothek – Information, 2023
The working group Evidence-Based Medicine (AG-EBM), which was established within the German Medical Library Association (AGMB) in 2019, continued its activities in 2022/2023 on a regular basis. At numerous virtual training sessions and the meeting at the
Buroh, Sabine, Cascant Ortolano, Lorena, von Gernler, Marc   +2 more
doaj   +1 more source

Wakefield Area Working Evaluation Framework - Literature Review [PDF]

, 2012
The Wakefield Metropolitan District Council (MDC) Area Working programme offers a radical and innovative approach to service improvement and redesign with the aim of better meeting community needs and addressing inequalities. Community participation is a
South, J, Warwick-Booth, L
core  

A protocol for a systematic review of clinical guidelines and published systematic reviews on the early detection of oral cancer [PDF]

, 2016
Background: The predicted increase in incidence of oral cavity cancer (OCC) coupled with high mortality and poor prognosis – particularly when diagnosed at a late/advanced stage – highlights the need for prevention and early detection/screening to ...
Al Bulushi, Naeema M., Conway, David I., Gibson, John, Macpherson, Lorna M.D., Ross, Alastair J., Worlledge-Andrew, Heather   +5 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Corticosteroid Administration to Prevent Complications of Anterior Cervical Spine Fusion: A Systematic Review. [PDF]

, 2018
Study Design: Systematic review. Objectives: Anterior cervical approach is associated with complications such as dysphagia and airway compromise. In this study, we aimed to systematically review the literature on the efficacy and safety of corticosteroid
Abedi, Aidin, Bonaki, Hirbod Nasiri, Jazayeri, Seyed Behnam, Rahimi-Movaghar, Vafa, Vaccaro, Alexander R., Zadegan, Shayan Abdollah   +5 more
core   +1 more source

The effectiveness of teamwork training on teamwork behaviors and team performance : A systematic review and meta-analysis of controlled interventions [PDF]

, 2017
The objective of this study was to conduct a systematic review and meta-analysis of teamwork interventions that were carried out with the purpose of improving teamwork and team performance, using controlled experimental designs.
Beauchamp, Mark R., Eys, Mark, McEwan, Desmond, Ruissen, Geralyn R., Zumbo, Bruno D.   +4 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source