Results 71 to 80 of about 498,912 (261)

Exploring search strategy for systematic literature review: evidence from the International Journal of Management Reviews

Business: Theory and Practice
Systematic literature reviews (SLRs) advance management theory and practice by synthesizing knowledge in a structured and transparent manner. However, inconsistent reporting of search strategies limits replicability and methodological rigor.
Marek Szarucki, Andriejus Sadauskis, Alma Mačiulytė-Šniukienė, Oskar Kosch   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Employee motivation in current literature: a systematic search

Entrepreneurship and Sustainability Issues
The main objective of this article is to systematise approaches to motivation in current professional literature and identify key factors influencing employee motivation, thereby contributing to both theoretical understanding and practical improvement of
Iveta Kmecová, Kateřina Jíchová
doaj   +1 more source

The impact of patient, intervention, comparison, outcome (PICO) as a search strategy tool on literature search quality: a systematic review

Journal of the Medical Library Association, 2018
Objective: This review aimed to determine if the use of the patient, intervention, comparison, outcome (PICO) model as a search strategy tool affects the quality of a literature search.
Mette Brandt Eriksen, Tove Faber Frandsen   +1 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Identifying studies evaluating susceptibility factors for chemical health assessments: A case study focused on methylmercury developmental neurotoxicity

Environment International
Identifying susceptibility factors for adverse health effects from chemical exposures is an important aspect of characterizing human health impacts. However, to date, an efficient approach for identifying these factors has not been established.
Deborah Segal, Rebecca Nachman, Onyemaechi Nweke, Elizabeth Radke, Geanine Brunson, Bita Khoshhal, G. Nicole Helguero, Leonid Kopylev   +7 more
doaj   +1 more source

Information sources for obesity prevention policy research: a review of systematic reviews

Systematic Reviews, 2017
Background Systematic identification of evidence in health policy can be time-consuming and challenging. This study examines three questions pertaining to systematic reviews on obesity prevention policy, in order to identify the most efficient search ...
Rosie Hanneke, Sabrina K. Young
doaj   +1 more source