Results 111 to 120 of about 535,118 (293)

Insulin sensitisers in the treatment of non-alcoholic fatty liver disease : a systematic review [PDF]

, 2011
Non-alcoholic fatty liver disease (NAFLD) is closely linked with obesity and the prevalence of NAFLD is about 17% to 33% in the Western world. There is a strong association of NAFLD with insulin resistance and, hence, insulin sensitisers have been tried.
C Clar, Henderson, R., Gurung, T., N Waugh, N Sattar, N Ghouri, Clar, C., Sattar, Naveed, Sattar, N., Fraser, A., T Gurung, Gurung, T. (Tara), D Shyangdan, A Fraser, Shyangdan, D., D Preiss, Waugh, Norman, Shyangdan, D. (Deepson), R Henderson, Ghouri, N., Preiss, D., Waugh, N.   +21 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Systematic Observation of Emotional Regulation in the School Classroom: A Contribution to the Mental Health of New Generations. [PDF]

Int J Environ Res Public Health, 2023
Alarcón-Espinoza M, Samper-Garcia P, Anguera MT.   +2 more
europepmc   +1 more source

Random weighting estimation for systematic error of observation model in dynamic vehicle navigation

, 2016
The Kalman filter requires kinematic and observation models not contain any systematic error. Otherwise, the resultant navigation solution will be biased or even divergent.
Shesheng Gao (19970619), Aleksandar Subic (12580519), Yongmin Zhong (18031702), Chengfan Gu (19010417), Wenhui Wei (176525)   +4 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Towards Predictive Analysis of Behavior and Sports Using LINCE PLUS 4 Software

Apunts: Educación Física y Deportes
The evolution of new technologies and the rise of artificial intelligence are already affecting how we carry out everyday tasks. Until now, developing a systematic observational study has been an intense and demanding process for researchers, and there ...
Alberto Soto-Fernández, Oleguer Camerino, Xavier Iglesias, Marta Castañer, Daniel Lapresa, M.T Anguera   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

SOCCER VAR: Development of an observational instrument for the analysis of VAR related incidents in soccer

Motricidade
Existing literature evidence reveals a significant gap in the use of Video Assistant Referees (VAR) in soccer, particularly regarding the availability of VAR observational methodology resources as a rigorous tool for analysing incidents. The aim of this
Magna Leilane Silva, Daniel Barreira, Jorge Campaniço   +2 more
doaj   +1 more source

The efectiveness of imagery rescripting and reprocessing therapy on cognitive abilities, distress tolerance and symptoms of obsessive-compulsive disorder (OCD) in women

مجله علوم روانشناختی, 2021
Background: Obsessive-compulsive disorder is one of the most common and debilitating psychological disorders. Numerous studies have examined the effectiveness of cognitive-behavioral therapies and third generation on the improvement of obsessive ...
maryam zabet, jahanger karami, kamran yazdanbakhse   +2 more
doaj  

Accuracy of paper-and-pencil systematic observation versus computer-aided systems. [PDF]

Behav Res Methods, 2023
Virues-Ortega J, Casas CD, Martin N, Tarifa-Rodriguez A, Hidalgo AJR, Cox AD, Navarro Guzmán JI.   +6 more
europepmc   +1 more source