Results 171 to 180 of about 535,118 (293)

Method for Observing SMOKing and vaping bEhaviours (MOSMOKE): development and validation of a systematic observation tool. [PDF]

BMJ Open
Benton JS, Berg S, Kapadi A, Bendel N, Jerram J, French DP.   +5 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Pharmaceutical Analysis of Inpatient Prescriptions: Systematic Observation of Hospital Pharmacists' Practices in the Early User-Centered Design Phase. [PDF]

JMIR Hum Factors
Butruille J, Cirnat N, Alaoui M, Saracco J, Cousein E, Chaniaud N.   +5 more
europepmc   +1 more source

Systematic Observation of Meteors

Scientific American, 1915
openaire   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Corrigendum: The incidence of periungual desquamation and thrombocytosis in Kawasaki disease and the importance of systematic observation in the subacute phase. [PDF]

Front Pediatr
Kim BJ, Choi A, Kim SI, Han JW.
europepmc   +1 more source

Screening for autism spectrum disorder in a naturalistic home setting using the systematic observation of red flags (SORF) at 18-24 months. [PDF]

Autism Res, 2020
Dow D, Day TN, Kutta TJ, Nottke C, Wetherby AM.   +4 more
europepmc   +1 more source

Systematic observation of coach feedback in elite youth volleyball

, 2014
The purpose of the study was to examine the relationship of coach feedback during time-outs to the performance of 16-18 year old volleyball players in competitive match play.
Mann, Mark
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source