Results 181 to 190 of about 535,118 (293)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Corrigendum: Observational Studies in Male Elite Football: A Systematic Mixed Study Review

open access: yesFrontiers in Psychology, 2019
Maria Preciado   +3 more
doaj   +1 more source

Review: Noelie Rodríguez & Alan Ryave (2002). Systematic Self-Observation

open access: yes, 2010
Systematic Self-Observation vermittelt eine Zusammenschau der 13jährigen Arbeit der Autor(inn)en, indem sie die Chancen und Grenzen ihrer Methode der systematischen Selbstbeobachtung diskutieren.
Chaparro, Hernán
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Systematic observation-based diagnosis of atrioventricular nodal reentrant tachycardia with a bystander concealed nodoventricular pathway. [PDF]

open access: yesJ Arrhythm
Nagashima K   +21 more
europepmc   +1 more source

Childhood Observation

open access: yes, 2008
Discussing the role of observation in the Early Years environment, this title helps Early Years students and practitioners understand the principles and ethical guidelines of observation and assessment methods, and encourages them to take a critical ...

core  

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