Results 101 to 110 of about 5,145,453 (383)
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Systemic analysis of production scenarios for bioethanol produced from ligno-cellulosic biomass [abstract] [PDF]
Biotechnologie, Agronomie, Société et Environnement, 2010 Defining alternatives for non-renewable energy sources constitutes a priority to the development of our societies. One of these alternatives is biofuels production starting from energy crops, agricultural wastes, forest products or wastes.
Ghysel, F. +5 more
doaj
Infection and Drug Resistance, 2023 Honglei Ma,1 Yuqun Wang,1 Junhong Liu,1 Linping Du,1 Xiaodong Wang,2 Yingliang Wang2 1Affiliated Hospital of Weifang Medical University, School of Clinical Medicine, Weifang Medical University, Weifang, Shandong Province, People’s Republic of China ...
Ma H +5 more
doaj
Systemic risk in dynamical networks with stochastic failure criterion
, 2014 Complex non-linear interactions between banks and assets we model by two time-dependent Erd\H{o}s Renyi network models where each node, representing bank, can invest either to a single asset (model I) or multiple assets (model II).
Bertella, M. +5 more
core +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Journal of Inflammation Research, 2023 Mingyang Du,1,* Lili Xu,1,* Xiaohao Zhang,2 Xianjun Huang,3 Hui Cao,1 Feng Qiu,1 Wenya Lan,1 Haibo Jiang1 1Cerebrovascular Disease Center, Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu Province, 210029, People ...
Du M +7 more
doaj
Markets, Systemic Risk, and the Subprime Mortgage Crisis [PDF]
, 2008 The recent subprime mortgage meltdown is undermining financial market stability and has the potential to cause a true systemic breakdown, collapsing the world\u27s financial systems like a row of dominoes.
Schwarcz, Steven L.
core +1 more source