Results 91 to 100 of about 2,206,550 (269)

LP-012 Patients with systemic lupus erythematosus and hyperproduction of antibodies to anti-U1RNP

Lupus Science and Medicine, 2023
Oxana Desinova, Olga Koneva, Rushana Shayakhmetova, Lidia Ananyeva, Liudmila Garzanova, Olga Ovsyannikova, Mayya Starovoytova   +6 more
doaj   +1 more source

A Comprehensive Review of Treatment Outcomes in Lichen Planus Pigmentosus

Clinical Dermatology Review
Lichen Planus Pigmentosus (LPP) has been a topic of debate and extensive research both with respect to its existence and its treatment. Many treatment options have evolved from topical to systemic each one emerging as an effective treatment in one or the
Rashmi Singh, Rajnish Kumar, Tulika Rai
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Enrico Castellani and the 1972-1973 experiments: grid, decentralisation and transparency in Lavagna and Topologema

piano b
The aim of the article is to investigate some works produced by Enrico Castellani in the early 1970s. In the light of the theoretical elaborations conceived by Castellani in the 1960s and during the following decades, the article aims to reread in ...
Michele Giuliano Cipolla
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Team-based motivational engagement intervention in young people with first-episode psychosis: the EYE-2 cluster RCT with economic and process evaluation

Health and Social Care Delivery Research
Background Early Intervention in Psychosis services improves outcomes for young people with psychosis, but 25% disengage in the first 12 months with costs to their mental health.
Kathryn Greenwood, Christopher Iain Jones, Nahel Yaziji, Andy Healey, Carl May, Stephen Bremner, Richard Hooper, Shanaya Rathod, Peter Phiri, Richard de Visser, Tanya Mackay, Gergely Bartl, Iga Abramowicz, Jenny Gu, Rebecca Webb, Sunil Nandha, Belinda Lennox, Louise Johns, Paul French, Jo Hodgekins, Heather Law, James Plaistow, Rose Thompson, David Fowler, Philippa Garety, Anastacia O’Donnell, Michelle Painter, Rebecca Jarvis, Stuart Clark, Emmanuelle Peters   +29 more
doaj   +1 more source

Hydroxychloroquine-associated retinal toxicity in juvenile-onset systemic lupus erythematosus: A single-center experience

Medicine Science
Hydroxychloroquine (HCQ) is a fundamental therapy in juvenile-onset systemic lupus erythematosus (SLE), yet data on HCQ-related retinal toxicity in children are limited and primarily extrapolated from adult studies.
Seyma Turkmen, Betul Sozeri
doaj   +1 more source

Ocular manifestation of rheumatoid arthritis-different forms and frequency. [PDF]

Bosn J Basic Med Sci, 2010
Zlatanović G, Veselinović D, Cekić S, Zivković M, Dorđević-Jocić J, Zlatanović M.   +5 more
europepmc   +1 more source