Results 11 to 20 of about 1,195,397 (240)

Serum cytokines to predict systemic lupus erythematosus clinical and serological activity

Clinical and Translational Science, 2022
We aimed to explore the role of interleukin (IL)‐6, interferon‐gamma (IFNγ), IL‐10, and tumor necrosis factor (TNF) as predictors of systemic lupus erythematosus (SLE) clinical and serological activity, and their correlation with the treatment received ...
Victor Moreno‐Torres, Raquel Castejón, María Martínez‐Urbistondo, Ángela Gutiérrez‐Rojas, Jose Vázquez‐Comendador, Pablo Tutor, Pedro Durán‐del Campo, Susana Mellor‐Pita, Silvia Rosado, Juan‐Antonio Vargas‐Núñez   +9 more
doaj   +1 more source

Role of MUC1 rs4072037 polymorphism and serum KL-6 levels in patients with antisynthetase syndrome

Scientific Reports, 2021
Mucin 1/Krebs von den Lungen-6 (KL-6) is proposed as a serum biomarker of several interstitial lung diseases (ILDs), including connective tissue disorders associated with ILD. However, it has not been studied in a large cohort of Caucasian antisynthetase
Sara Remuzgo-Martínez, Belén Atienza-Mateo, J. Gonzalo Ocejo-Vinyals, Fernanda Genre, Verónica Pulito-Cueto, Víctor M. Mora-Cuesta, David Iturbe-Fernández, Leticia Lera-Gómez, Raquel Pérez-Fernández, Diana Prieto-Peña, Juan Irure, Fredeswinda Romero-Bueno, Olga Sanchez-Pernaute, Rodrigo Alonso-Moralejo, Laura Nuño, Gema Bonilla, Esther F. Vicente-Rabaneda, Ignacio Grafia, Sergio Prieto-González, Javier Narvaez, Ernesto Trallero-Araguas, Albert Selva-O’Callaghan, Spanish Biomarkers of Antisynthetase Syndrome Consortium, Spanish Biomarkers of Interstitial Lung Disease Consortium, Oreste Gualillo, Lorenzo Cavagna, José M. Cifrián, Elisabetta A. Renzoni, Santos Castañeda, Raquel López-Mejías, Miguel A. González-Gay   +30 more
doaj   +1 more source

Serum, but Not Saliva, CXCL13 Levels Associate With Infiltrating CXCL13+ Cells in the Minor Salivary Gland Lesions and Other Histologic Parameters in Patients With Sjögren’s Syndrome

Frontiers in Immunology, 2021
Recent studies suggest that elevated CXCL13 serum levels in patients with primary Sjögren’s syndrome (pSS) associate with minor salivary gland (MSG) histologic features, disease severity, as well as high-risk status for non-Hodgkin lymphoma (NHL ...
Loukas Chatzis, Loukas Chatzis, Andreas V. Goules, Andreas V. Goules, Ioanna E. Stergiou, Ioanna E. Stergiou, Michael Voulgarelis, Michael Voulgarelis, Athanasios G. Tzioufas, Athanasios G. Tzioufas, Efstathia K. Kapsogeorgou, Efstathia K. Kapsogeorgou   +11 more
doaj   +1 more source

Childhood versus adulthood-onset autoinflammatory disorders: myths and truths intertwined

Reumatismo, 2013
Autoinflammatory disorders are characterized by spontaneous episodes of systemic inflammation deriving from inherited defects of the innate immune system.
L. Cantarini, A. Vitale, O.M. Lucherini, I. Muscari, F. Magnotti, G. Brizi, B. Frediani, G.D. Sebastiani, M. Galeazzi, D. Rigante   +9 more
doaj   +1 more source

Quantitative videocapillaroscopy correlates with functional respiratory parameters: a clue for vasculopathy as a pathogenic mechanism for lung injury in systemic sclerosis

Arthritis Research & Therapy, 2018
Background To determine whether lung involvement is related to microvascular perturbations, nailfold videocapillaroscopy (NVC) was performed in patients with systemic sclerosis (SSc).
Alfredo Guillén-Del-Castillo, Carmen Pilar Simeón-Aznar, Eduardo L. Callejas-Moraga, Carles Tolosa-Vilella, Serafín Alonso-Vila, Vicente Fonollosa-Pla, Albert Selva-O’Callaghan   +6 more
doaj   +1 more source

Practical Applicability of the ISARIC-4C Score on Severity and Mortality due to SARS-CoV-2 Infection in Patients with Type 2 Diabetes

Medicina, 2022
Background and objectives. There is a bidirectional relationship between SARS-CoV-2 infection and diabetes mellitus (DM), as people with DM are more vulnerable, and SARS-CoV-2 infections worsen the prognosis in these patients.
Oana Albai, Mirela Frandes, Alexandra Sima, Bogdan Timar, Adrian Vlad, Romulus Timar   +5 more
doaj   +1 more source

Preliminary safety and efficacy profile of prucalopride in the treatment of systemic sclerosis (SSc)-related intestinal involvement: results from the open label cross-over PROGASS study

Arthritis Research & Therapy, 2017
Background Prokinetics are used to treat enteric dismotility symptoms in systemic sclerosis (SSc) patients, but they often lack adequate efficacy. The most effective prokinetics belonging to the serotonin (5-HT4) receptor agonists class were withdrawn ...
Barbara Vigone, Monica Caronni, Adriana Severino, Chiara Bellocchi, Anna Rita Baldassarri, Mirella Fraquelli, Gaia Montanelli, Alessandro Santaniello, Lorenzo Beretta   +8 more
doaj   +1 more source

Characteristics of COVID-19 infection and antibody formation in patients known at a tertiary immunology department

Journal of Translational Autoimmunity, 2021
Background: Knowledge about COVID-19 infections is expanding, although knowledge about the disease course and antibody formation in patients with an auto-immune disease or immunodeficiency is not fully unraveled yet.
Niels A.D. Guchelaar, Jan A.M. van Laar, Maud A.W. Hermans, Tim B. van der Houwen, Sibel Atmaca, Maurits S. van Maaren, Zana Brkic, Paul L.A. van Daele, Virgil A.S.H. Dalm, P. Martin van Hagen, Saskia M. Rombach   +10 more
doaj   +1 more source

Usefulness of the hemogram as a measure of clinical and serological activity in systemic lupus erythematosus

Journal of Translational Autoimmunity, 2022
Background and objectives: Systemic Lupus Erythematosus (SLE) follow-up is based on clinical, and analytical parameters. We aimed to determine the differences between the Neutrophil-to-lymphocyte ratio (NLR), Platelet-to-lymphocyte ratio (PLR) and Red ...
Víctor Moreno-Torres, Raquel Castejón, Susana Mellor-Pita, Pablo Tutor-Ureta, Pedro Durán-del Campo, María Martínez-Urbistondo, José Vázquez-Comendador, Ángela Gutierrez-Rojas, Silvia Rosado, Juan A. Vargas-Nuñez   +9 more
doaj   +1 more source

Nervous System Lyme Disease

Infectious Disease Clinics of North America, 1998
Lyme disease, the multi-system infection caused by the tick-borne spirochaete Borrelia burgdorferi, can involve the nervous system, most commonly causing, alone or in combination, lymphocytic meningitis or abnormalities of cranial or peripheral nerves, the latter most typically presenting as a painful radicular syndrome.
openaire   +9 more sources