Results 81 to 90 of about 1,311,352 (316)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Detection of high cardiovascular risk patients with ankylosing spondylitis based on the assessment of abdominal aortic calcium as compared to carotid ultrasound

Arthritis Research & Therapy, 2018
Background This study aimed to determine whether, besides carotid ultrasound (US), a lateral lumbar spine radiography may also help identify ankylosing spondylitis (AS) patients at high risk of cardiovascular (CV) disease.
Javier Rueda-Gotor, Fernanda Genre, Alfonso Corrales, Ricardo Blanco, Patricia Fuentevilla, Virginia Portilla, Rosa Expósito, Cristina Mata, Trinitario Pina, Carlos González-Juanatey, Luis Rodriguez-Rodriguez, Miguel A. González-Gay   +11 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Managing Pneumonia Due to Rare Non-Fermenting Gram-Negative Bacteria: Epidemiology, Risk Factors and Therapeutic Strategies

Antibiotics
Pneumonia remains a leading cause of morbidity and mortality worldwide, with bacterial pathogens contributing significantly to its burden. While Pseudomonas aeruginosa and Acinetobacter baumannii complex are well-recognized non-fermenting Gram-negative ...
Alessandro Capone, Francesca Gavaruzzi, Valentina Antonelli, Claudia Rotondo, Samir Al Moghazi, Emanuela Caraffa, Pierangelo Chinello, Carla Fontana, Stefania Cicalini   +8 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Epidemiology of Kawasaki disease in the population of the Caribbean Island of Martinique, 2013–2019

BMC Pediatrics
Purpose Kawasaki disease (KD) is a vasculitis of the large and medium vessels. Its description and epidemiology in the Afro-descendant (AD) population and in Latin America and the Caribbean (LAC) are limited.
Doline Monges, Melanie Brard, Hugues Lucron, Sarah Pallara-Sirven, Aurélie Armougon, Hanine Mansour, Claudia Hospice, Christophe Deligny, Yves Hatchuel, Lindsay Osei, Moustapha Dramé, Arthur Felix   +11 more
doaj   +1 more source

Patients with Ankylosing Spondylitis and Low Disease Activity because of Anti-TNF-Alpha Therapy Have Higher TRAIL Levels Than Controls: A Potential Compensatory Effect

Mediators of Inflammation, 2014
Objective. TRAIL is a potential biomarker of cardiovascular (CV) disease. Ankylosing spondylitis (AS) is a chronic inflammatory disease associated with metabolic syndrome (MeS) and accelerated atherosclerosis.
Fernanda Genre, Raquel López-Mejías, Javier Rueda-Gotor, José A. Miranda-Filloy, Begoña Ubilla, Beatriz Carnero-López, Natalia Palmou-Fontana, Inés Gómez-Acebo, Ricardo Blanco, Trinitario Pina, Rodrigo Ochoa, Carlos González-Juanatey, Javier Llorca, Miguel A. González-Gay   +13 more
doaj   +1 more source

Systemic amyloidosis in England: an epidemiological study.

, 2013
Epidemiological studies of systemic amyloidosis are scarce and the burden of disease in England has not previously been estimated. In 1999, the National Health Service commissioned the National Amyloidosis Centre (NAC) to provide a national clinical ...
Smith, CJ, Banypersad, SM, Whelan, CJ, Venner, CP, Dungu, J, Pinney, JH, Lachmann, HJ, Taube, JB, Gillmore, JD, Gibbs, SD, Hawkins, PN, Wechalekar, AD   +11 more
core  

Periodontitis and systemic diseases: A literature review

, 2022
The present study focus on the association of the periodontitis and the systematic diseases. Periodontics and the systemic diseases has increased over the years. The present study focus on different types of the systemic diseases and its association with
Upadhyay, Palak, Bhavishyavani, Machireddy, Mustilwar, Rachita, Mishra, Supriya, Darade, Lalit, Bagde, Hiroj   +5 more
core   +1 more source

Nails in systemic disease

Indian Journal of Dermatology, Venereology, and Leprology, 2011
Nail abnormalities secondary to systemic disease could be classified as nail abnormalities associated with systemic disease, disease of specific organ system or associated with syndromes and genodermatoses. Because nail findings are easily observable and yield valuable information, careful examination of nails could be an important diagnostic tool for ...
openaire   +2 more sources