Results 91 to 100 of about 1,901,654 (301)

Glucocorticoids—All-Rounders Tackling the Versatile Players of the Immune System [PDF]

open access: yes, 2019
Glucocorticoids regulate fundamental processes of the human body and control cellular functions such as cell metabolism, growth, differentiation, and apoptosis.
Agarwal   +268 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Epidemiology of Kawasaki disease in the population of the Caribbean Island of Martinique, 2013–2019

open access: yesBMC Pediatrics
Purpose Kawasaki disease (KD) is a vasculitis of the large and medium vessels. Its description and epidemiology in the Afro-descendant (AD) population and in Latin America and the Caribbean (LAC) are limited.
Doline Monges   +11 more
doaj   +1 more source

The Prevalence of Atrophic Tongue in Patients Referring to Isfahan Health Clinics [PDF]

open access: yes, 2016
Introduction:Atrophic tongue or smooth tongue is resulted from atrophy of the filiform papillae. The tongue often shows a shiny red appearance. This lesion may be seen in many systemic diseases.
Hashimi,, Mardani,, Mohamadi,
core  

It takes two to tango: NAD+ and sirtuins in aging/longevity control [PDF]

open access: yes, 2016
The coupling of nicotinamide adenine dinucleotide (NAD+) breakdown and protein deacylation is a unique feature of the family of proteins called ‘sirtuins.’ This intimate connection between NAD+ and sirtuins has an ancient origin and provides a ...
Guarente, Leonard, Imai, Shin-ichiro
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Markers Of Insulin Resistance and Their Clinical Implications In Patients with Type 2 Diabetes and Metabolic Dysfunction-Associated Steatotic Liver Disease

open access: yesDiabetes, Metabolic Syndrome and Obesity
Oana Albai,1– 3 Adina Braha,1– 3 Romulus Timar,1– 3 Sandra Lazar,3– 6 Simona Popescu,1– 3 Bogdan Timar1– 3 1Department of Second Internal Medicine—Diabetes, Nutrition, Metabolic Diseases, and Systemic Rheumatology, “Victor Babes” University of Medicine ...
Albai O   +5 more
doaj  

Diagnostic value of neutrophil-to-lymphocyte, platelet-to-lymphocyte, and lymphocyte-to-monocyte ratios for assessing organ and multiorgan involvement in sarcoidosis: a retrospective single-center study

open access: yesFrontiers in Medicine
BackgroundSarcoidosis is a heterogeneous disease lacking reliable biomarkers for organ involvement. Indices derived from the complete blood count (CBC), including the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and ...
Estefanía Díaz-Martín   +10 more
doaj   +1 more source

Circular 40 [PDF]

open access: yes, 1980
For cooperation and assistance in the work reported here, we gratefully acknowledge Dr. William Burgoyne, State of Alaska Division of Environmental Conservation and Mr. Delon Brown, USDA, Alaska Crop and Livestock Reporting Service.
Bleicher, David P.   +2 more
core  

Periodontal disease and systemic disease [PDF]

open access: yesJournal of the Royal Society of Medicine, 2014
Iain L C, Chapple   +3 more
openaire   +2 more sources

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