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Parkinson's Disease and Systemic Inflammation [PDF]
Parkinson's Disease, 2011 Peripheral inflammation triggers exacerbation in the central brain's ongoing damage in several neurodegenerative diseases. Systemic inflammatory stimulus induce a general response known as sickness behaviour, indicating that a peripheral stimulus can ...
Carina C. Ferrari, Rodolfo Tarelli
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The Expression of ARMCX1 in Gastric Cancer Contributes to Prognosis and Influences Chemotherapy
Journal of Immunology Research, 2023 The altered expression of ARMCX1 in patients with gastric cancer has been reported frequently, yet its correlation to prognosis and chemotherapy needs to be unveiled.
Changheng Lv +8 more
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Neutrophil-Derived IL-6 Potentially Drives Ferroptosis Resistance in B Cells in Lupus Kidney
Mediators of Inflammation, 2023 Ferroptosis resistance is vital for B cell development, especially in inflammatory diseases, yet the underlying mechanism is still unclear. In this study, based on the scRNA-seq technique and flow cytometry, we discovered a proportion of neutrophils ...
Zechen Wang +9 more
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Endothelial Cells Potentially Participate in the Metastasis of Triple-Negative Breast Cancer
Journal of Immunology Research, 2022 Inhibition of triple-negative breast cancer metastasis has long been a challenge, mainly due to the difficulty in identifying factors that contribute to this process.
Yanfei Ma +14 more
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Clinical Status of Cardiac Rehabilitation Manners and Models
Cardiology Research and Practice, 2022 Cardiac rehabilitation, which combines cardiology and preventive medicine, is an important part of treatment for cardiovascular diseases. Systematically, cardiac rehabilitation, including simultaneously inhibiting endothelial injury and promoting ...
Wei Wei +10 more
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IL-2-Agonist-Induced IFN-γ Exacerbates Systemic Anaphylaxis in Food Allergen-Sensitized Mice
Frontiers in Immunology, 2020 Food allergies are common, costly and potentially life-threatening disorders. They are driven by Th2, but inhibited by Th1 reactions. There is also evidence indicating that IL-2 agonist treatment inhibits allergic sensitization through expansion of ...
Christopher W.M. Link +14 more
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Heterogeneity in NK Cell Subpopulations May Be Involved in Kidney Cancer Metastasis
Journal of Immunology Research, 2022 Although substantial progress has been made in the immunotherapy of kidney cancer, its efficacy varies from patient to patient, with many responding suboptimally or even developing metastases.
Zhengfang Liang +6 more
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Anaphylatoxins spark the flame in early autoimmunity
Frontiers in Immunology, 2022 The complement system (CS) is an ancient and highly conserved part of the innate immune system with important functions in immune defense. The multiple fragments bind to specific receptors on innate and adaptive immune cells, the activation of which ...
Jovan Schanzenbacher +3 more
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C5aR1 Activation Drives Early IFN-γ Production to Control Experimental Toxoplasma gondii Infection
Frontiers in Immunology, 2020 Toxoplasma gondii (T. gondii) is a parasite infecting animals and humans. In intermediate hosts, such as humans or rodents, rapidly replicating tachyzoites drive vigorous innate and adaptive immune responses resulting in bradyzoites that survive within ...
Daria Briukhovetska +8 more
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IL-10 revisited in systemic lupus erythematosus
Frontiers in Immunology, 2022 IL-10 is a cytokine with pleiotropic functions, particularly known for its suppressive effects on various immune cells. Consequently, it can limit the pathogenesis of inflammatory diseases, such as multiple sclerosis (MS), inflammatory bowel disease ...
Swayanka Biswas +2 more
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