Results 231 to 240 of about 936,764 (268)

Role of the Melanocortin System in Inflammation

Annals of the New York Academy of Sciences, 2006
Abstract:  In recent years, scientific interest in melanocortins (MC) has progressively increased due to their wide range of effects and expression on various tissues.Primarily discovered as mediators of skin pigmentation, recent research has shown their important roles in various body functions, such as energy homeostasis, sexual function, and ...
Christian, Maaser, Klaus, Kannengiesser, Torsten, Kucharzik   +2 more
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The Kinin System in Inflammation

1993
Bradykinin and related kinins are important mediators of most kinds of inflammation. Mechanisms of kinin production in injury, infection and immune system activation are discussed. Bradykinin antagonists show great promise for development of new drugs for inflammation.
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Systemic inflammation after trauma

Injury, 2007
Trauma is still one of the main reasons for death among the population worldwide. Mortality occurring early after injury is due to "first hits", including severe organ injury, hypoxia, hypovolaemia or head trauma. Massive injury leads to activation of the immune system and the early inflammatory immune response after trauma has been defined as systemic
Andreas, Lenz, Glen A, Franklin, William G, Cheadle   +2 more
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Spinal opioid systems in inflammation

Inflammation Research, 1995
Until recently, basic science studies, both behavioural and electrophysiological, have concentrated on the antinociceptive actions of opioids primarily gauged against acute nociceptive responses. However, of more relevance to clinical situations are the actions of opioids in more persistent/prolonged pain states.
L, Stanfa, A, Dickenson
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Central nervous system inflammation

European Journal of Anaesthesiology, 2008
Activation of inflammation is the hallmark of pathological processes that follow acute injury. This process is mediated by inflammatory cytokines and adhesion molecules that reside on the surface of endothelium, leucocyte and inflammatory cells. Attenuation of the adhesion cascade has been the subject of several basic science and clinical trials in the
S G, Soriano, S, Piva
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Systemic inflammation and Alzheimer's disease

Biochemical Society Transactions, 2011
A number of studies demonstrate disturbances of the central innate immune system in AD (Alzheimer's disease). In animal and human studies, there is evidence of close communication between systemic and central innate immune systems. Animal models of neurodegeneration show evidence of an exaggerated central innate immune response following systemic ...
Clive, Holmes, Joe, Butchart
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Inflammation, Sepsis, and the Coagulation System

Hämostaseologie
AbstractSepsis has been a major health problem for centuries and it is still the leading cause of hospital deaths. Several studies in the past decades have identified numerous biochemical abnormalities in severe cases, and many of these studies provide evidence of the perturbation of the hemostatic system.
János, Kappelmayer, Ildikó Beke, Debreceni, Zsolt, Fejes, Béla, Nagy   +3 more
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Controlling the complement system in inflammation

Immunopharmacology, 1997
Inappropriate or excessive activation of the complement system can lead to harmful, potentially life-threatening consequences due to severe inflammatory tissue destruction. These consequences are clinically manifested in various disorders, including septic shock, multiple organ failure and hyperacute graft rejection.
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Sauna bathing and systemic inflammation

European Journal of Epidemiology, 2017
We aimed to investigate whether frequency of sauna bathing is associated with the levels of serum C-reactive protein. C-reactive protein is a leading blood marker of systemic inflammation. The study consisted of 2084 men (42-60 years) without acute or chronic inflammation.
Laukkanen Jari Antero, Laukkanen Tanjaniina   +1 more
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Encephalopathy of Infection and Systemic Inflammation

Journal of Clinical Neurophysiology, 2013
This review will discuss several intracranial infections and sepsis-associated encephalopathy. Intracranial infections and inflammation of interest to the neurologist and EEG technicians include viral and autoimmune encephalitides; bacterial, fungal, and other meningitides; cerebritis; and brain abscess and subdural empyema.
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