Results 41 to 50 of about 2,399,468 (309)

Overall Structural Alteration of Gut Microbiota and Relationships with Risk Factors in Patients with Metabolic Syndrome Treated with Inulin Alone and with Other Agents: An Open-Label Pilot Study

Mediators of Inflammation, 2022
Objective. The relative contribution of some products with prebiotic effects, such as inulin, together with medications specific to the human gut microbiome has not been comprehensively studied. The present study determined the potential for manipulating
Ruiping Tian, Jiahui Hong, Jingjie Zhao, Dengyuan Zhou, Yangchen Liu, Zhenshan Jiao, Jian Song, Yu Zhang, Lingzhang Meng, Ming Yu   +9 more
doaj   +1 more source

Intestinal flora induces depression by mediating the dysregulation of cerebral cortex gene expression and regulating the metabolism of stroke patients

Frontiers in Molecular Biosciences, 2022
Post-stroke depression (PSD) is a common cerebrovascular complication characterized by complex pathogenesis and poor treatment effects. Here, we tested the influence of differentially expressed genes (DEGs), non-targeted metabolites, and intestinal ...
Xuebin Li, Xuebin Li, Guangshun Han, Jingjie Zhao, Xiaohua Huang, Yun Feng, Junfang Huang, Xuequn Lan, Xiaorui Huang, Zechen Wang, Jiajia Shen, Siyuan He, Qiuhao Li, Jian Song, Jian Song, Jie Wang, Jie Wang, Lingzhang Meng, Lingzhang Meng   +18 more
doaj   +1 more source

Infection and inflammation and the coagulation system [PDF]

Cardiovascular Research, 2003
Severe infection and inflammation almost invariably lead to hemostatic abnormalities, ranging from insignificant laboratory changes to severe disseminated intravascular coagulation (DIC). Systemic inflammation results in activation of coagulation, due to tissue factor-mediated thrombin generation, downregulation of physiological anticoagulant ...
Levi, M., Keller, T.T., Gorp, E. van, Cate, H. ten   +3 more
openaire   +3 more sources

Complement Has Brains—Do Intracellular Complement and Immunometabolism Cooperate in Tissue Homeostasis and Behavior?

Frontiers in Immunology, 2021
The classical liver-derived and serum-effective complement system is well appreciated as a key mediator of host protection via instruction of innate and adaptive immunity.
Natalia Kunz, Claudia Kemper, Claudia Kemper   +2 more
doaj   +1 more source

S100A9 Derived From Myeloma Associated Myeloid Cells Promotes TNFSF13B/TNFRSF13B-Dependent Proliferation and Survival of Myeloma Cells

Frontiers in Oncology, 2021
Multiple myeloma (MM) is a lethal hematological malignancy characterized by abundant myeloid cells in the microenvironment that fuel tumor progression. But the mechanism by which myeloid cells support myeloma cells has not been fully explored.
Lingzhang Meng, Lingzhang Meng, Qiang Tang, Jingjie Zhao, Zechen Wang, Liuzhi Wei, Liuzhi Wei, Qiuju Wei, Qiuju Wei, Lianfei Yin, Shiguan Luo, Jian Song, Jian Song   +12 more
doaj   +1 more source

Tumor-Infiltrated CD8+ T Cell 10-Gene Signature Related to Clear Cell Renal Cell Carcinoma Prognosis

Frontiers in Immunology, 2022
Clear cell renal cell carcinoma (ccRCC) usually affects multiple organs (e.g., bone and brain), and patient prognosis is usually poor. Although it is known that CD8+ T cell infiltration can potentially alleviate ccRCC progression, few studies have ...
Jie Wang, Jie Wang, Feifan Huang, Jingjie Zhao, Peng Huang, Junhua Tan, Meiying Huang, Ruiying Ma, Yu Xiao, Siyuan He, Zechen Wang, Jiajia Shen, Heming Lu, Lingzhang Meng, Lingzhang Meng   +14 more
doaj   +1 more source

Translational Systems Biology of Inflammation

PLoS Computational Biology, 2008
Inflammation is a complex, multi-scale biologic response to stress that is also required for repair and regeneration after injury. Despite the repository of detailed data about the cellular and molecular processes involved in inflammation, including some understanding of its pathophysiology, little progress has been made in treating the severe ...
Yoram Vodovotz, Márie Csete, John Bartels, Steven Chang, Gary An   +4 more
openaire   +5 more sources

ADAM-10 Regulates MMP-12 during Lipopolysaccharide-Induced Inflammatory Response in Macrophages

Journal of Immunology Research, 2022
A disintegrin and metalloprotease 10 (ADAM-10), a member of the ADAM protease family, has biological activities related to TNF-α activation, cell adhesion, and migration, among other functions.
Yan Jiang, Qiming Gong, Jinmei Huang, Yuanxun Gong, Qiang Tang, Dalong Wei, Qianli Tang, Jingjie Zhao, Jian Song, Lingzhang Meng   +9 more
doaj   +1 more source

Treatment of periodontitis and endothelial function [PDF]

, 2007
Background: Systemic inflammation may impair vascular function, and epidemiologic data suggest a possible link between periodontitis and cardiovascular disease.
Deanfield, John, Nibali, Luigi, Suvan, Jean, Vallance, Patrick, Storry, Clare, Nibali, L., Donald, Ann, D'Aiuto, F., Storry, C., Parkar, Mohamed, Vallance, P., Hingorani, A.D., Tonetti, Maurizio S., Parkar, M., Deanfield, J., Hingorani, Aroon D., Suvan, J., Donald, A., D'Aiuto, Francesco, Tonetti, M.S.   +19 more
core   +1 more source

A Novel Role for C5a in B-1 Cell Homeostasis

Frontiers in Immunology, 2018
B-1 cells constitute a unique subpopulation of lymphocytes residing mainly in body cavities like the peritoneal cavity (PerC) but are also found in spleen and bone marrow (BM).
Katharina Bröker, Julia Figge, Albert F. Magnusen, Rudolf A. Manz, Jörg Köhl, Jörg Köhl, Christian M. Karsten   +6 more
doaj   +1 more source