Results 101 to 110 of about 32,366 (248)

Systemic Arthritis in Children: A Review of Clinical Presentation and Treatment

open access: yesInternational Journal of Inflammation, 2012
Systemic juvenile idiopathic arthritis (sJIA) constitutes a small part of juvenile idiopathic arthritis (JIA), yet has a disproportionally higher rate of mortality. Despite being grouped under JIA, it is considered to be a multifactorial autoinflammatory
R. Gurion   +2 more
doaj   +1 more source

Mydriasis as a Secondary Effect in Patients With HLA‐B27–Associated Uveitis

open access: yesMedicine Advances, EarlyView.
HLA‐B27‐associated acute anterior uveitis causes significant inflammation of the iris and anterior chamber, which disrupts normal parasympathetic control and results in increased sympathetic tone leading to pupil dilation (mydriasis). This finding can sometimes resemble herpetic uveitis, making a clinical context and careful evaluation crucial for ...
Saim Mahmood Khan   +6 more
wiley   +1 more source

INFLIXIMAB IN TREATMENT OF ACTIVE JUVENILE ARTHRITIS

open access: yesВопросы современной педиатрии, 2012
The article includes the results of observation of patients with resistant forms of juvenile arthritis, who have received treatment with infliximab in the period of time since 2004 till 2011.
E. S. Zholobova   +6 more
doaj   +1 more source

“You can't do this, you've arthritis":Exploring the experiences of education and employment of young people with arthritis [PDF]

open access: yes, 2018
Introduction: Vocational development is an integral component of adolescence with several key educational transitions occurring during this stage of life.
Farre, Albert   +4 more
core   +2 more sources

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

open access: yesRheumatology &Autoimmunity, EarlyView.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

New treatment strategies for growth failure caused by chronic inflammation in children [PDF]

open access: yes, 2013
Chronic inflammation during childhood often leads to impaired bone growth and reduced height in adulthood. Interleukin-1β (IL-1β), interleukin-6 (IL-6) and the tumour necrosis factor-α (TNF-α) are pro-inflammatory cytokines up-regulated during chronic ...
Fernández Vojvodich, Paola
core   +1 more source

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria

open access: yesAllergy, EarlyView.
ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
T. Zuberbier   +221 more
wiley   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter   +20 more
wiley   +1 more source

Autoinflammation and autoimmunity in systemic juvenile idiopathic arthritis [PDF]

open access: yesProceedings of the National Academy of Sciences, 2015
Juvenile idiopathic arthritis (JIA) encompasses a range of phenotypes of joint inflammation that begin in childhood. The most distinctive and potentially most severe of these is systemic JIA (sJIA), an intensely inflammatory disease characterized by high spiking fevers and evanescent rashes that sometimes progresses to a devastating chronic ...
openaire   +2 more sources

Histopathological features of gastrointestinal mucosal biopsies in children with juvenile idiopathic arthritis [PDF]

open access: yes, 2016
BACKGROUND: The association between inflammatory bowel disease and joint involvement is well established. There is a paucity of data describing histopathological features of the gut in relation to juvenile idiopathic arthritis (JIA).
Borrelli, O   +7 more
core   +1 more source

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