Results 121 to 130 of about 32,366 (248)

Long-term outcomes and predictors of biologic treatment in systemic juvenile idiopathic arthritis in a single-center experience in Thailand

Indian Journal of Rheumatology, 2018
Background: The outcomes of systemic juvenile idiopathic arthritis (SJIA) vary from mild disability to mortality. Due to the socioeconomic problems in Thailand, the delay in receiving some medications, especially biologic agents, might affect the ...
Sirisucha Soponkanaporn, Suphaneewan Jaovisidha, Soamarat Vilaiyuk   +2 more
doaj   +1 more source

ProNGF-p75NTR axis plays a proinflammatory role in inflamed joints. A novel pathogenic mechanism in chronic arthritis [PDF]

, 2017
To identify the role of mature nerve growth factor (mNGF), its immature form proNGF and their receptors in arthritis ...
Benedetti, Fabrizio De, Bracci-laudiero, Luisa, Caiello, Ivan, Magni-manzoni, Silvia, Manni, Luigi, Manzo, Antonio, Marafon, Denise Pires, Minnone, Gaetana, Prencipe, Giusi, Soligo, Marzia   +9 more
core   +1 more source

Immune cell infiltration correlates with intestinal permeability, inflammation, and gastrointestinal symptoms in type 1 diabetes

Journal of Diabetes Investigation, EarlyView.
In individuals with type 1 diabetes, immune cell infiltration in the colon mucosa tended to correlate with fecal and systemic markers of intestinal permeability and inflammation, as well as gastrointestinal symptoms. These findings suggest that low‐grade gut immune activation might link the intestinal barrier dysfunction with systemic endotoxin ...
Polina Zalizko, Reinis Isaks, Leonora Pahirko, Aleksejs Fedulovs, Eduards Krustins, Jurijs Nazarovs, Sergejs Dubencovs, Hanne Salmenkari, Markku Lehto, Kaspars Jēkabsons, Una Riekstiņa, Per‐Henrik Groop, Niina Sandholm, Jeļizaveta Sokolovska   +13 more
wiley   +1 more source

tRF‐30‐FP18LPMBQ4NK in Systemic Juvenile Idiopathic Arthritis: A Promising Diagnostic and Disease Activity Biomarker

Annals of the New York Academy of Sciences, EarlyView.
ABSTRACT Diagnosing systemic juvenile idiopathic arthritis (sJIA) poses significant challenges. Accumulating evidence has indicated that tRNA‐derived fragments (tRFs) play integral roles in the pathogenesis of numerous diseases. Plasma samples were collected from individuals diagnosed with sJIA and healthy controls (HCs) from two medical centers and ...
Jiqian Huang, Yuting Pan, Jing Jin, Xiaoyan Shao, Wenjie Zheng, Zhidan Fan, Haiguo Yu   +6 more
wiley   +1 more source

Proteinuria in children with juvenile idiopathic arthritis: Making the case for early urinary screening

Saudi Journal of Kidney Diseases and Transplantation, 2017
Systemic onset juvenile idiopathic arthritis (SOJIA) can be associated with proteinuria due to various renal pathologies. We report two pediatric cases with SOJIA and nephrotic syndrome secondary to renal amyloidosis, a very rare complication in children.
Anshuman Saha, Priya Pais, Arpana Aprameya Iyengar, Anila Kurien Abraham   +3 more
doaj   +1 more source

Differentially Expressed Salivary miRNAs in Temporomandibular Disorders

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective Temporomandibular disorders (TMDs) are heterogeneous conditions of unclear aetiology involving the temporomandibular joint, masticatory muscles and neural tissues. Limited understanding of their pathogenesis hampers accurate diagnosis and targeted treatment. Therefore, this study aimed to identify salivary microRNA (miRNA) signatures
Karolina Elżbieta Kaczor‐Urbanowicz, Mohammad Aziz, Holly Wilhalme, Sharon Aronovich, Elizabeth Rae Hatfield, Tara Aghaloo, Sherwin Arman, Aida Mohammadi, Mohammed Husain, Sotirios Tetradis, David Elashoff, Matteo Pellegrini, David T. W. Wong, Sunil Kapila   +13 more
wiley   +1 more source

Retrospective Analysis of Efficacy and Safety of Tocilizumab Treatment in Children with Severe Systemic Juvenile Idiopathic Arthritis: 12-month Follow-up

Вопросы современной педиатрии, 2013
Aim: to carry out a retrospective analysis of efficacy and safety of tocilizumab treatment in children with severe resistant forms of systemic juvenile idiopathic arthritis.
A. A. Baranov, E. I. Alexeeva, R. V. Denisova, S. I. Valieva, T. M. Bzarova, K. B. Isaeva, T. V. Steptsova, E. V. Mitenko, E. G. Chistyakova, A. N. Fetisova   +9 more
doaj   +1 more source

Age‐Related Osseous Measures of the Temporomandibular Joint and Mandibular Ramus During Childhood Assessed by Magnetic Resonance Imaging

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective This study aimed to provide age‐related osseous measures of the temporomandibular joints (TMJs) and mandibular ramus in asymptomatic children and adolescents and to develop percentile reference data for ramus height. Material and Methods A retrospective cross‐sectional study was conducted on 133 asymptomatic participants (67 males ...
Juliet Zuying Shen, Maurice Molnar, Dominik Alois Ettlin, Daniel Beat Wiedemeier, Christian Johannes Kellenberger   +4 more
wiley   +1 more source

Macrophage activation syndrome during pregnancy as a fatal complication of systemic idiopathic arthritis

Акушерство, гинекология и репродукция
According to the current concept, juvenile arthritis with a systemic onset (systemic juvenile idiopathic arthritis, sJIA) and adult­onset Still's disease (ASD) are considered as rare autoinflammatory diseases, with the underlying immunopathogenesis being
P. A. Shesternya, V. B. Tskhay, M. I. Bazina, I. V. Matveeva   +3 more
doaj   +1 more source

THE STRUCTURE AND CLINICAL MANIFESTATIONS OF JUVENILE IDIOPATHIC ARTHRITIS IN CHILDREN IN KRASNODAR

Кубанский научный медицинский вестник, 2018
Aim. The research was conducted to study the structure (variants, sexual and age characteristics) and manifestations of articular syndrome in children with juvenile idiopathic arthritis in Krasnodar.Materials and methods.
A. V. Burlutskaya, N. V. Savelyeva, S. V. Polischuk   +2 more
doaj   +1 more source