Results 241 to 250 of about 456,719 (283)
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New insights into the immunopathogenesis of systemic lupus erythematosus
Nature Reviews Rheumatology, 2016George C Tsokos +2 more
exaly +2 more sources
Nature Genetics, 2015 Systemic lupus erythematosus (SLE) is a genetically complex autoimmune disease characterized by loss of immune tolerance to nuclear and cell surface antigens.
James Bentham +2 more
exaly +2 more sources
New England Journal of Medicine, 2008
In their review article, Rahman and Isenberg (Feb. 28 issue)1 emphasize the role of anti–double-stranded DNA antibodies in the pathogenesis of systemic lupus erythematosus. Such antibodies also occur, however, in 23 to 64% of patients with type 1 autoimmune hepatitis, depending on the assay used.2 Interestingly, 36% of patients with type 1 autoimmune ...
Pappas G +2 more
+5 more sources
In their review article, Rahman and Isenberg (Feb. 28 issue)1 emphasize the role of anti–double-stranded DNA antibodies in the pathogenesis of systemic lupus erythematosus. Such antibodies also occur, however, in 23 to 64% of patients with type 1 autoimmune hepatitis, depending on the assay used.2 Interestingly, 36% of patients with type 1 autoimmune ...
Pappas G +2 more
+5 more sources
Platelets release mitochondrial antigens in systemic lupus erythematosus
Science Translational Medicine, 2021Platelets are a source of extracellular DNA and mitochondrial antigens in systemic lupus erythematosus. An unexpected source of antigens Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease that can affect multiple organs ...
I. Melki +21 more
semanticscholar +1 more source
Journal of the American Academy of Nurse Practitioners, 1992
The reported change in the incidence of systemic lupus erythematosus (SLE) is mainly due to a greater awareness of the disease, and to the introduction of serological detection methods such as the LE cell assay and subsequently a variety of other antinuclear antibody assays.
A J, Swaak, J C, Nossent, R J, Smeenk
openaire +4 more sources
The reported change in the incidence of systemic lupus erythematosus (SLE) is mainly due to a greater awareness of the disease, and to the introduction of serological detection methods such as the LE cell assay and subsequently a variety of other antinuclear antibody assays.
A J, Swaak, J C, Nossent, R J, Smeenk
openaire +4 more sources
The Journal of the American Dental Association, 1980
A case of osteomyelitis of the mandible in a patient with systemic lupus erythematosus is described. Both the disease process and the treatment modalities must be understood for correct management.
S J, Samuelson +2 more
openaire +4 more sources
A case of osteomyelitis of the mandible in a patient with systemic lupus erythematosus is described. Both the disease process and the treatment modalities must be understood for correct management.
S J, Samuelson +2 more
openaire +4 more sources
Drugs of Today, 2002
Systemic lupus erythematosus is a pleomorphic, autoimmune disorder of unknown cause that can afflict all parts of the body. New insights into its pathogenesis, the employment of preventive measures and combinations of immunosuppressive therapy, as well as the introduction of biologics, are beginning to alter the prognosis and improve the quality of ...
openaire +2 more sources
Systemic lupus erythematosus is a pleomorphic, autoimmune disorder of unknown cause that can afflict all parts of the body. New insights into its pathogenesis, the employment of preventive measures and combinations of immunosuppressive therapy, as well as the introduction of biologics, are beginning to alter the prognosis and improve the quality of ...
openaire +2 more sources
Best Practice & Research Clinical Rheumatology, 2010
Systemic lupus erythematosus (SLE) is one of the most diverse autoimmune diseases as it may affect any organ in the body and display a broad spectrum of clinical and immunological manifestations. Epidemiological studies have identified marked differences in the prevalence and course of SLE between genders, and across different ages, races and ...
Sean, O'Neill, Ricard, Cervera
openaire +2 more sources
Systemic lupus erythematosus (SLE) is one of the most diverse autoimmune diseases as it may affect any organ in the body and display a broad spectrum of clinical and immunological manifestations. Epidemiological studies have identified marked differences in the prevalence and course of SLE between genders, and across different ages, races and ...
Sean, O'Neill, Ricard, Cervera
openaire +2 more sources
Medical Clinics of North America, 1986
Systemic lupus erythematosus is a multisystem inflammatory disease characterized by autoantibody production. Recent investigations are providing insights into the immunoregulatory disturbances underlying this disease, and are clarifying the approach to diagnosis and treatment.
openaire +3 more sources
Systemic lupus erythematosus is a multisystem inflammatory disease characterized by autoantibody production. Recent investigations are providing insights into the immunoregulatory disturbances underlying this disease, and are clarifying the approach to diagnosis and treatment.
openaire +3 more sources
Annals of Internal Medicine, 2013
Systemic lupus erythematosus (lupus) is characterized by aberrant activity of the immune system, leading to variable clinical symptoms. Lupus is more prevalent in African American women and women in other ethnic minority groups. Diagnosing, treating, and identifying novel therapies for lupus is challenging because of its genetic and phenotypic ...
Marianthi, Kiriakidou +3 more
openaire +2 more sources
Systemic lupus erythematosus (lupus) is characterized by aberrant activity of the immune system, leading to variable clinical symptoms. Lupus is more prevalent in African American women and women in other ethnic minority groups. Diagnosing, treating, and identifying novel therapies for lupus is challenging because of its genetic and phenotypic ...
Marianthi, Kiriakidou +3 more
openaire +2 more sources